ANSTO Nuclear-based science benefitting all Australians
Research Hub

ANSTO's research capabilities, led by the OPAL nuclear research reactor and associated instruments provide access to users investigating areas as diverse as materials, life sciences, climate change and mining/engineering.

Bio-analytics

 

Bio-analysis can mean different things to different people: at ANSTO LifeSciences we measure metabolites and endogenous compounds in biological fluids and analyse biologically active compounds, often using radio-tracers.

 

Bio-analytical techniques can be used to monitor occupational and environmental exposure to chemicals by determining concentrations in biofluids, food or environmental samples, they can be used in forensic toxicology, and in therapeutic drug monitoring.

 

Prof Richard Banati leads our research in Bio-analytics, with support from our researchers in cell, radiation, and molecular biology.


Capabilities

  

Biodistribution in cellsMembrane biophysics
  • Lipid bilayer synthesis and analysis
  • Electrophysiology
  • Impedeance spectrometry 
    Contact scientists: Richard BanatiGuo Jun Liu
Molecular biologyNanodosimetry simulation
  • Nucleic acid analysis using real time PCR and high resolution melt analysis 
    Contact scientists: Winnie KamRyan Middleton 
  • Genetic engineering (molecular cloning, transfection, transduction) 
    Contact scientist: Ryan Middleton
  • Protein expression  
    Contact scientist: Ryan Middleton

     
  • Computer simulation using Geant4 to model the radiation effect based on the actual biological setup
    Contact scientist: Winnie Kam 
Physiological functional analysis in cellsRadiation biology and (Radio)ligand biochemistry
  • Irradiation of mammalian samples using ionizing (Gamma, X-ray) or non-ionizing radiation (UV)  
    Contact scientist: Winnie Kam
  • Compound solubility determination 
    Contact scientist: Nick Howell