ANSTO's research capabilities, led by the OPAL nuclear research reactor and associated instruments provide access to users investigating areas as diverse as materials, life sciences, climate change and mining/engineering.
Publications and Conference Presentations 2007
Peer-reviewed papers
Bourdier, T., Poisnel, G., Dhilly, M., et al. Synthesis and biological evaluation of N-substituted quinolinimides, as potential ligands for in vivo imaging studies of delta-opioid receptors. Bioconjug Chem. 2007;18(2):538-548.
Boutin, H., Chauveau, F., Thominiaux, C., et al. 11C-DPA-713: A novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation. J Nucl Med. 2007;48(4):573-581.
Boutin, H., Chauveau, F., Thominiaux, C., et al. In vivo imaging of brain lesions with [11C]CLINME, a new PET radioligand of peripheral benzodiazepine receptors. Glia. 2007;55(14):1459-1468.
Callaghan, P. D., Owens, W. A., Javors, M. A., Sanchez, T. A., Jones, D. J., Irvine, R. J., Daws, L. C. In vivo analysis of serotonin clearance in rat hippocampus reveals that repeated administration of p-methoxyamphetamine (PMA), but not 3,4-methylenedioxymethamphetamine (MDMA), leads to long-lasting deficits in serotonin transporter function. J Neurochem. 2007;100:617-627.
Gallezot, J-D., Bottlaender, M. A., Delforge, J., et al. Quantification of cerebral nicotinic acetylcholine receptors by PET using 2-[lsqb]18F[rsqb]fluoro-A-85380 and the multiinjection approach. J Cereb Blood Flow Metab. 2007;28(1):172-189.
Huang, X. F., du Bois, T. M., Hsu, C., Eftimovska, J., Tan, Y. Y., Zavitsanou, K., Newell, K. A., Deng, C. NMDA receptor hypofunction during early brain development: Relevance to schizophrenia, Schizo Bull. 2007; 33(2): 317-317.
Liu, X., Banister, S., Christie, M., Banati, R., Meikle, S., Coster, M., Kassiou, M. Trishomocubanes: Novel σ ligands modulated cocaine-induced behaviour effects. Eur J Pharmacol. 2007;555:37-42.
Mo, L., Wu, H. Y., Baldock. C. Absolute activity determination of 198Au solid source using 4pb-g coincidence counting corrected by Monte-Carlo calculation. IEEE Trans Nuc Sci. 2007; 54: 3(2)677-683.
Newell, K., Zavitsanou, K., Jew, S. K., Huang, X. F. Alterations in muscarinic and GABA receptors in the posterior cingulate cortex in schizophrenia. Prog Neuro-Psychoph. 2007;31(1):225-233.
Newell, K. A., Zavitsanou, K., Huang, X. F. The posterior cingulate cortex: A site of altered neural circuitry in schizophrenia and NMDA receptor hypofunction, Schizo Bull. 2007; 33(2): 321-321.
Newell, K. A., Zavitsanou, K., Huang, X. F. Short and long term changes in NMDA receptor binding in mouse brain following chronic phencyclidine treatment. J Neural Transm. 2007; 114(8): 995-1001.
Newell, K. A., Zavitsanou, K., Huang, X. F. Opposing short and long-term effects on muscarinic M1/4 receptor binding following chronic phencyclidine treatment. J Neurosci Res. 2007; 85: 1358-1363.
Pham, T. Q., Berghofer, P., Liu, X., et al. Preparation and biologic evaluation of a novel radioiodinated benzylpiperazine, 123I-MEL037, for malignant melanoma. J Nucl Med. 2007;48(8):1348-1356.
Pham, T. Q., Greguric, I., Liu, X., et al. Synthesis and evaluation of novel radioiodinated benzamides for malignant melanoma. J Med Chem. 2007;50(15):3561-3572.
Quinlivan, M., Chalon, S., Vergote, J., et al. Decreased vesicular acetylcholine transporter and [alpha]4[beta]2 nicotinic receptor density in the rat brain following 192 IgG-saporin immunolesioning. Neurosci Lett. 2007;415(2):97-101.
Quinlivan, M., Chalon, S., Guilloteau, D., Kassiou, M., Katsifis, A., Henderson, J. Diminished nicotinic receptor density and an impairment in attention but not memory in the 192 IgG-saporin model of AD. Neurodegen Dis. 2007;4(Suppl. 1):183-264.
Quinn, H., Matsumoto, I., Callaghan, P. D., Long, L. E., Arnold, J. C., Gunasekaran, N., Thompson, M. R., Dawson, B., Mallet, P. E., Kashem, M. A., Matsda-Matsumoto, H., Iwazki, T., McGregor, I. S. Adolescent rats find repeated THC (delta-9-tetrahydrocannabinol) less aversive that adult rats but display greater residual cognitive deficits and changes in hippocampal protein expression following exposure. Neuropsychopharmacol. 2008;33(5):1113-1126.
Reischl, G., Dorow, D., Cullinane, C., Katsifis, A., Roselt, P., Binns, D., Hicks, R. Imaging of tumor hypoxia with [124I]IAZA in comparison with [18F]FMISO and [18F]FAZA First small animal PET results. J Pharm and Pharmaceut Sci 2007;10(2):203-211.
Thompson, M. R., Callaghan, P. D., Hunt, G. E., Cornish, J. L., McGregor, I. S. A role for oxytocin and 5-HT1A receptors in the prosocial effects of 3,4 methylenedioxymethamphetamine ("ecstasy"). Neurosci. 2007;146(2):509-514.
Thominiaux, C., Mattner, F., Greguric, I., et al. Radiosynthesis of 2-[6-chloro-2-(4-iodophenyl)imidazo[1,2-a]pyridin-3-yl]-N-ethyl-N-[11C]methyl-acetamide, [11C]CLINME, a novel radioligand for imaging the peripheral benzodiazepine receptors with PET. J Labelled Compd Rad. 2007;50(4):229-236.
Zavitsanou, K., Nguyen, V., Greguric, I., Chapman, J., Ballantyne, P., Katsifis, A. Detection of apoptotic cell death in the thymus of dexamethasone treated rats using [123I]Annexin V and in situ oligonucleotide ligation. J Mol Histol. 2007;38(4):313-319.
Zavitsanou, K., Nguyen, V., Salvadori, P., Smith, S. Radiopharmacy and radiopharmaceuticals: 2007 update. QJ Nucl Med Mol Imag (Invited Editorial). 2007;51:3-5.
Zavitsanou, K., Nguyen, V., Greguric, I., Chapman, J., Ballantyne, P., Katsifis, A. Detection of apoptotic cell death in the thymus of dexamethasone treated rats using [123I] Annexin V and in situ oligo ligation. J Mol Histol. 2007; 38: 313-319.
Zavitsanou, K., Nguyen, V. H., Han, M., Huang, X. F. Effects of typical and atypical antipsychotic drugs on rat brain muscarinic receptors. Neurochem Res. 2007; 32: 525-532.
Conference Proceedings
Bourdier, T., Pham, T., Fookes, C., Greguric, I., Katsifis, A. (2007) Synthesis of S-(2-[18F]-fluoroethyl)-L-methionine for tumour imaging. XVIIth International Symposium on Radiopharmaceutical Sciences, April 30 - May 4 2007, Aachen, Germany.
Deng, C., Eftimovska, J., Zavitsanou, K., Huang, X. F (2007) Phencyclidine induces apoptosis in the brain of neonatal but not adolescent and adult rats, submitted, IBRO World Congress of Neuroscience, Melbourne, 12-17 of July, 2007
Han, M., Deng, C., Zavitsanou, K., Tan, Y. Y., Huang, X. F (2007) Effects of antipsychotics on muscarinic M1 receptor mRNA expression in the rat brain, submitted, IBRO World Congress of Neuroscience, Melbourne, 12-17 of July, 2007
Homes, T. P., Mattner, F., Keller, P. A., Katsifis, A. (2007) Synthesis and in vivo evaluation of a novel [123I] indolglyoxylamide for the peripheral benzodiazepine binding sites. XVIIth International Symposium on Radiopharmaceutical Sciences, April 30 - May 4 2007, Aachen, Germany.
Huang, X. F., South, T., Zavitsanou, K., Chao, D. (2007) A negative association between the CB1 mRNA expression and high fat intake during the course of diet-induced obesity in mice, Annual Meeting for the Society for Neuroscience, November 2007, USA.
Huang, X. F., du Bois, T. M., Newell, K. A., Zavitsanou, K., Deng, C. (2007) A rodent model of NMDA receptor hypofunction for study of schizophrenia. The 7th Biennial Meeting of the Chinese Society for Neuroscience, Hanhzhou, China, October 2007. Neuroscience Bulletin 23 (Supplement 1): 81.
Huang, X. F., du Bois, T. M., Hsu, C-W., Eftimovska, J., Tan, Y. Y., Zavitsanou, K., Newell, K. A., Deng, C. (2007) NMDA receptor hypofunction during early brain development: relevance to schizophrenia, submitted, International Congress on Schizophrenia Research, Colorado 28th of March-1st of April
Huang, X. F., du Bois, T. M., Newell, K. A., Zavitsanou, K., Hsu, C. W., Eftimovska, J., Tan, Y. Y., Deng, C. (2007) Long-tern consequences of early brain development disruption on neurochemical balance and behavior, submitted, IBRO World Congress of Neuroscience, Melbourne, 12-17 of July, 2007
Le, V. S., Nguyen, C. D., Bui, V. C., Vo, C. H. Preparation of zirconium- and titanium based inorganic polymer sorbents and their application in 99Mo/99mTc & 188W/188Re radionuclide generator technology. (2007) Third Research Co-ordination Meeting on "Development of Generator Technologies for Therapeutic radionuclides", October 8-12 2007, Daejeon, Korea.
Mattner, F., Pham, T., Fookes, C., Greguric, I., Berghofer, P., Ballantyne, P., Liu, X., Jackson, T., Dikic, B., Shepherd, R., Katsifis, A. (2007) In vivo evaluation of a [18F] labelled imidazopyridazine, for the study of the peripheral benzodiazepine binding sites using PET. XVIIth International Symposium on Radiopharmaceutical Sciences, April 30 - May 4 2007, Aachen, Germany.
Mattner, F., Pham, T., Greguric, I., Berghofer, P., Ballantyne, P., Liu, X., Dikic, B., Jackson, T., Dolle, F., Katsifis, A. (2007) Labelling and in vivo evaluation of the [123I] labelled imidazopyridine-3-acetamide, CLINME for the study of the peripheral benzodiazepine binding sites. XVIIth International Symposium on Radiopharmaceutical Sciences, April 30 - May 4 2007, Aachen, Germany.
Newell, K. A., Dawson, A., du Bois, T., Zavitsanou, K., Huang, X. F. (2007) Region-specific CB1 receptor changes in the rodent brain following NMDA receptor antagonism, submitted, IBRO World Congress of Neuroscience, Melbourne, 12-17 of July, 2007
Newell, K. A., Zavitsanou, K., Huang, X-F. (2007) The posterior cingulate cortex: a site of altered neural circuitry in schizophrenia and NMDA hypofunction, submitted, International Congress on Schizophrenia Research, Colorado 28th of March-1st of April, 2007
Pham, T., Mattner, F., Fookes, C., Greguric, I., Berghofer, P., Ballantyne, P., Liu, X., Shepherd, R., Jackson, T., Katsifis, A. (2007) Synthesis and evaluation of [18F] labelled imidazopyridines, for the study of peripheral benzodiazepine binding sites using PET. International Symposium on Radiopharmaceutical Sciences. XVIIth International Symposium on Radiopharmaceutical Sciences, April 30 - May 4 2007, Aachen, Germany.
Pham, T., Fookes, C., Liu, X., Greguric, I., Bourdier, T., Katsifis, A. (2007) Synthesis of [18F]fluorine labelled imidazo[1,2b] pyridazine as potential probes for the study of peripheral benzodiazepine binding sites using PET. XVIIth International Symposium on Radiopharmaceutical Sciences, April 30 May- 4 2007, Aachen, Germany.
Quinlivan, M., Chalon, S., Guilloteau, D., Kassiou, M., Katsifis, A., Henderson, J. (2007) Diminished nicotinic receptor density and an impairment in attention but not memory in the 192 Igg-Saporin model of AD. 8th International Conference; Alzheimer's and Parkinson's Diseases: Progress and New Perspectives; March 14-18 2007, Salzburg, Austria.
Zaw, M. (2007) Oxidation profile of arsenic, iron, manganese and uranium in tailings dam samples using x-ray absorption near-edge structure spectroscopy. 15th Australian Conference on Nuclear and Complementary Techniques of Analysis (NCTA) and 9th Vacuum Society of Australia Congress (AINSE). November 21-23 2007 (ISBN 0 9758434 2 7), 353-357. The University of Melbourne, Melbourne, Australia.
