ANSTO Nuclear-based science benefitting all Australians
Research Hub

ANSTO's research capabilities, led by the OPAL nuclear research reactor and associated instruments provide access to users investigating areas as diverse as materials, life sciences, climate change and mining/engineering.

Publications and Conference Presentations 2008

 

Peer-reviewed papers

 

Alexiev, D., Mo, L., Prokopovich, D. A., Smith, M. L., Matuchovac, M. Comparison of LaBr3:Ce and LaCl3:Ce with NaI(Tl) and cadmium zinc telluride (CZT) detectors. IEEE Trans. Nucl Sci. 2008; 55(3):1174-1177.


Arlicot, N., Katsifis, A., Harreau, L., Mattner, F., Vergote, J., Duval, S., Bodard, S., Guilloteau, D., Chalon, S. Evaluation of CLINDE as potent translocator potein (18 kDa) SPECT radiotracer reflecting the degree of neuroinflammation in a rat model of excitotoxic lesion. Eur J Nuc Med Mol Imag. 2008; 35(12):2203-11. 


Bignell, L. J., Smith, M. L., Alexiev, D. Hashemi-Nezhad, S. R. Analysis of adhesive tape activation during reactor flux measurements. Nucl Eng Tech. 2008; 40:93-98.


Bignell, L. J., Mo, L., Smith, M. L., Alexiev, D., Hashemi-Nezhad, S. R. Monte Carlo simulation of a 198Au thin foil: The response of a 4 πβ-γ  detector. IEEE Trans Nucl Sci. 2008;  55:3550-3555


Bourdier, T.,  Fookes, C. J. R., Pham, T. Q., Greguric, I.,  Katsifis, A. Synthesis and stability of S-(2-[18F](fluoroethyl)-L-homocysteine for potential tumour imaging. J. Lab. Comp. Radiopharm. 2008, 51(13), 3700-3712.


Bourdier, T., Huiban, M., Huet, A., Sobrio, F., Fouquet, E., Perrio, C., Barré, L. Tetra- and monoorganotin reagents in palladium-mediated cross-coupling reactions for the labeling with carbon-11 of PET tracers. Synthesis. 2008(6):978-984.


Cornish, J. L., Clemens, K. J., Thompson, M. R., Callaghan, P. D., Dawson, B., McGreor, I. S. High ambient temperature increases intravenous methamphetamine self-administration on fixed and progressive ratio schedules in rats. J Psychopharmacol. 2008;22(1):100-110.


Dollé, F., Hinnen, F., Damont, A., Kuhnast, B., Fookes, C., Pham, T., Tavitian, B., Katsifis, A. Radiosynthesis of [18F]PBR111, a selective radioligand for imaging the translocator protein (18 kDa) with PET. J Labelled Compd Rad  Nov 2008.


Fookes, C. J. R., Pham, T. Q., Mattner, F., Greguric, I., Loc’h, C., Liu, X., Berghofer, P., Shepherd, R., Gregoire, M-C., Katsifis, A. Synthesis and biological evaluation of substituted [18F]Imidazo[1,2-a]pyridines and [18F]Pyrazolo[1,5-a]pyrimidines for the study of the peripheral benzodiazepine receptor using Positron Emission Tomography. J Med Chem. 2008;51(13):3700-3712.


Greguric, I., Pham, T. Q., Liu, X., Katsifis, A. Nicotinamide derivatives for imaging and therapy of melanoma. Provisional Patent 2008901989, 2008.


Han, M., Newell, K., Zavitsanou, K., Deng, C., Huang, X. F. Effects of antipsychotic  medication on muscarinic M1 mRNA expression in the rat brain. J Neurosci Res. 2008; 86(2): 457-464.


Hargreaves, S., Bignell, L. J., Lewis, R. A., Schoenherr, D., Saglam, M., Hartnagel, H. L. Investigation of p-GaAsSb as a THz emitter. J Electrochem Soc. 2008; 155(10): H734-H737.


Huang, X-F., Liu, Y., Rahardjo, G. L., Mclennan, P. L., Tapsell, L. C., Buttemer, W. A. Effects of diets high in whey, soy, red meat and milk protein on body weight maintenance in diet-induced obesity in mice. Nutr Dietet. 2008;65(s3):S53-S59.


Le, V. S., Morcos, N., Zaw, M., Pellegrini, P., Greguric, I. Alternative chromatographic processes for no-carrier added 177Lu radioisotope separation. I. Multi-column chromatographic process for clinically applicable, no-carrier added 177Lu radioisotope separation. J Radioanal Nucl Chem. 2008;277(3):663-673.


Le, V. S., Morcos, N., Zaw, M., Pellegrini, P., Greguric, I., Nevissi, A. Alternative chromatographic processes for no-carrier added 177Lu radioisotope separation. II. The conventional column chromatographic separation combined with HPLC for high purity, no-carrier added 177Lu radioisotope production. J Radioanal Nucl Chem. 2008;277(3):675-683.


Le, V. S., Pellegrini, P., Katsifis, A., Howse, J., Greguric, I. Radiochemical separation and quality assessment for the 68Zn target based 64Cu radioisotope production. J Radioanal Nucl Chem. 2008;277(2):451-466.


Le, V. S., Morcos, N. New SPE column packing material, retention assessment method and its application for the radionuclide chromatographic separation. J Radioanal Nucl Chem. 2008;277(3): 651-661.


Liu, X., Pham, T. Q., Berghofer, P., Chapman, J., Greguric, I., Mitchell, P., Mattner, F., Loc’h, C., Katsifis, A. Synthesis and evaluation of novel radioiodinated nicotinamides for malignant melanoma. Nucl Med Biol. 2008;35(7):769-781.


Mattner, F., Mardon, K., Katsifis, A. Pharmacological evaluation of [123I]-CLINDE: a radioiodinated imidazopyridine-3-acetamide for the study of peripheral benzodiazepine binding sites (PBBS). Eur J Nuc Med Mol Imag. 2008;35(4):779-789.


McGregor, I. S., Callaghan, P. D., Hunt, G. E. From ultrasocial to antisocial: a role for oxytocin in the acute reinforcing effects and lond-term advers consequences of drug use? Br J Pharmacol. 2008;154(2):358-368.


Prince, H. M., Wall, D. M., Ritchie, D., Honemann, D., Harrrison, S., Quach, H., Thompson, M., Hicks, R., Lau, E., Davison, J., Loudovaris, M., Moloney, J., Loveland, B., Bartholeyns, J., Katsifis, A., Mileshkin, L. In vivo tracking of dendritic cells in patients with multiple myeloma. J Immunother. 2008 Feb-Mar;31(2):166-79.


Qin, M. J., Mo, L., Alexiev, D., Cassette, P. Construction and implementation of a TDCR system at ANSTO. Appl Rad Isotopes. 2008;66(6-7):1033-1037.


Quinn, H., Matsumoto, I., Callaghan, P. D., Long, L. E., Arnold, J. C., Gunasekaran, N., Thompson, M. R., Dawson, B., Mallet, P. E., Kashem, M. A., Matsda-Matsumoto, H., Iwazki, T., McGregor, I. S. Adolescent rats find repeated THC (delta-9-tetrahydrocannabinol) less aversive that adult rats but display greater residual cognitive deficits and changes in hippocampal protein expression following exposure. Neuropsychopharmacol. 2008;33(5):1113-1126.


Smith, M. L., Bignell, L., Alexiev, D., Mo, L., Harrison, J. Evaluation of lead shielding for a gamma-spectroscopy system. Nucl Instrum Meth A. 2008;589(2):275-279.


Sobrio, F., Quentin, T., Dhilly, M., Bourdier, T., Tymciu, S., Debruyne, D., Barré, L. Radiosynthesis and ex vivo evaluation of [11C]-SIB-1553A as a PET radiotracer for beta4 selective subtype nicotinic acetylcholine receptor. Nucl Med Biol. 2008;35(3):377-85. Epub Jan 30 2008.


Thompson, M. R., Callaghan, P. D., Hunt, G. E., McGregor, I. S. Reduced sensitivity to MDMA-induced facilitation of social behaviour in MDMA pre-exposed rats. Prog Neuro-psychoph. 2008;32(4):1013-1021.


Zavitsanou, K., Nguyen, V. H., Newell, K., Ballantyne, P., Huang, X. F. Rapid cortico-limbic alterations in  AMPA receptor densities after administration of PCP: implications for schizophrenia. J Chem Neuroanat. 2008; 36: 71-76

 

 

Conference Proceedings

 

Alexiev, D. (2008). Report to the TC (IR) and the General Assembly of the APMP, November 2- 8, 2008, Jakarta, Indonesia.


Alexiev, D., Mo, L., Smith, M., Bignell, L., Steele, T. (2008). Lonising radiation physics at the Australian Nuclear Science and Technology Organisation. Metrology, resting and accreditation – breaking the trading barriers. International Symposium RMO2008, November, 2008, Cavat, Croatia.


Arlicot, N., Petit, E., Katsifis, A., Mattner, F., Divoux, D., Guilloteau, D., Bernaudin, M., Chalon, S. (2008). Detection and quantification of TSPO overexpression after permanent focal cerebral ischemia in the mouse using [125I]-CLINDE: an ex vivo autoradiographic study. 2008 World Molecular Imaging Congress, September 10-13, 2008, Nice, France


Bignell, L. J., Mo, L., Smith, M. L. , Alexiev, D. (2008). Quantitative uncertainty evaluation for Monte Carlo simulations of 123I decay in a liquid scintillation vial. Uncertainties and Activity Intercomparisons Workshop, at the Bureau International de Ponds et Measures, October, 2008, Paris, France.


Dalton, V. S., Wang, H. Q., Zavitsanou, K. (2008). Age-related effects of the synthetic cannabinoid, HU210, on body weight and cannabinoid receptor density in the rat brain. 10th Biennial Australasian Schizophrenia Conference, October 23-24, 2008, Lorne, Victoria. Abstracts 42(2): 62


Dedeurwaerdere, S., Myers, D., Vivash, L., Bouilleret, V., Sari Rusli, A. P., Retat, L., Binns, D., Roselt, P., Hicks, R. J., Katsifis, A., O'Brien, T., Gregoire, MC. (2008). In vivo 18F-Flumazenil PET and MRI imaging in the kainic acid model of temporal lobe epilepsy. World Molecular Imaging Conference, September 10-13, 2008, Nice, France.


Fookes, C., Homes, T., Pham, T., Mattner, F., Greguric, I., Liu, X., Keller, P., Katsifis, A. (2008) Synthesis and evaluation of novel [123I] and [18F] labelled pyrazolopyrimidines, for the study of Peripheral Benzodiazepine Receptor using PET and SPECT. 38th Annual Meeting of the Australia and New Zealand Society of Nuclear Medicine, May 1-6 2008, Gold Coast, Australia.


Fookes, C.. Pham, T., Mattner, F., Greguric, I., Liu, X., Berghofer, P., Shepherd, R., Katsifis, A. (2008). Synthesis and evaluation of [18F]PBR102 and [18F]PBR111. Novel ligands for imaging neurodegeneration and inflammation using PET. 38th Annual Meeting of the Australia and New Zealand Society of Nuclear Medicine, May 1-6 2008, Gold Coast, Australia.


Kench, P., Gregoire, M-C., Quinlivan, M., Lin, J., Mattner, F., Katsifis, A., Meikle, S. (2008) The use of multiple pinhole SPECT to measure the heterogeneity of small animal tumour models. 38th Annual Meeting of the Australia and New Zealand Society of Nuclear Medicine, May 1-6 2008, Gold Coast, Australia.


Le, V. S., Howse, J., Zaw, M., Pellegrini, P., Katsifis, A., Greguric, I. (2008) Alternative method for Cu-64 radioisotope production. 6th International Conference of Isotopes, May 12-16 2008, Seoul, South Korea.
 

Mattner, F., Berghofer, P., Shepherd, R., Howell, N., Pham, T., Bourdier, T., Ballantyne, P., Katsifis, A. (2008) Ex vivo pharmacological evaluation of the peripheral benzodiazepine receptor radioligand [123I]CLINDE in animal tumour model. 38th Annual Meeting of the Australia and New Zealand Society of Nuclear Medicine, May 1-6 2008, Gold Coast, Australia.


Mattner, F., Linares, D., Staykova, M., Ballantyne, P., Berghofer, P., Pham, T., Willenborg, D., Katsifis, A. (2008) Synthesis and evaluation of [123I]CLINDE a novel ligand for imaging of neurodegeneration and inflammation using SPECT. 38th Annual Meeting of the Australia and New Zealand Society of Nuclear Medicine, May 1-6 2008, Gold Coast, Australia.


Mattner, F., Linares, D., Staykova, M., Gregoire, M-C., Pham, T., Bourdier, T., Quinlivan, M., Callaghan, P., Willenborg, D., Katsifis, A. (2008) Evaluation of the PBR ligand [123I]CLINDE in an animal model of experimental autoimmune encephalomyelitis. 55th Annual Meeting of the Society of Nuclear Medicine, June 14-18, 2008, New Orleans, USA. J Nucl Med 49: 81P.


Mo, L. (2008). Standardisation of I123 using TDCR method. ICRM – Liquid Scintillation and Life Science meeting, National Physics Laboratory, November, 10-16, 2008, Teddington, UK.


Quinlivan, M., Gregoire, M-C., Mattner, F., Katsifis, A. (2008) The Peripheral Benzodiazepine Receptor ligand ClINME can delineate microglial activation similarly well with either SPECT or PET. 38th Annual Meeting of the Australia and New Zealand Society of Nuclear Medicine, May 1-6 2008, Gold Coast, Australia.


Retat, L., Bouilleret, V., Myers, D., Katsifis, A., Gregoire, MC. (2008). How does partial volume correction improve Bmax and Kdvr estimates in the rat brain imaging with 18F-Flumazenil?. World Molecular Imaging Conference, September 10-13, 2008, Nice, France.


Zavitsanou, K., Wang, H. Q., Dalton, V., Newson, P., Chahl, L. Receptor changes in rats treated as neonates with capsaicin- testing a potential animal model of aspects of schizophrenia, Proceedings of the 28th Annual Meeting of the Australian Neuroscience Society (Hobart 27-30th January 2008), ISSN No 1034-3237, Vol 18, pg 118.

 

Zavitsanou, K., Nguyen, V., Wang, H. Q., Dalton, V. S. (2008). Cannabinoid effects on 5HT1A receptor density and D2 related functionality in the adult rat brain. 10th Biennial Australasian Schizophrenia Conference, October 23-24, 2008, Lorne, Victoria. Abstracts 42(2): 44.


Zaw, M., Morcos, N., Pellegrini, P., Greguric, I., Nevissi, A., Le, V. S. (2008) Evaluation of HPLC parameters to optimise the yiels and purification of no-carrier added 177Lu and 176Yb targets. 6th International Conference of Isotopes, May 12-16 2008, Seoul, South Korea.