ANSTO Nuclear-based science benefitting all Australians
Research Hub

ANSTO's research capabilities, led by the OPAL nuclear research reactor and associated instruments provide access to users investigating areas as diverse as materials, life sciences, climate change and mining/engineering.

Publications and Conference Presentations 2012

 

Journals

 

Bourdier, T., Pham, T. Q., Henderson, D., Jackson, T., Lam, P., Izard, M., Katsifis, A. Automated radiosynthesis of [18F]PBR111 and [18F]PBR102 using the TracerLab FXFN and TracerLab MXFDG module for imaging the peripheral benzodiazepine receptor with PET. Applied Radiation and Isotopes, 70(1) 176-183 (2012)

 

Bowen, M. Y., Keats, K., Kendig, M. D., Cakic, V., Callaghan, P. D., McGregor, I. S. Aggregation in quads but not pairs of rats exposed to cat odor or bright light. Behavioural Processes, 90(3) 331-6 (2012)

 

Dalton, V. S., Verdurand, M., Walker, A., Hodgson, D. M., Zavitsanou, K. Synergistic effect between maternal infection and adolescent cannabinoid exposure on serotonin 5HT1A receptor binding in the hippocampus: Testing the “two hit” hypothesis for the development of schizophrenia. ISRN Psychiatry, 2012 451865 (2012)

 

Davies, J. B., Bosi, S. G., Baldock, C. Dosimetry aspects of a non-diffusing genipin-gelatin gel dosimeter. Radiation Physics and Chemistry, 83 19-27 (2012)

 

Davies, J. B., Bosi, S., Baldock, C. A genipin-gelatin gel dosimeter for radiation processing. Radiation Physics and Chemistry, 81(8) 1263-1265 (2012)

 

Dedeurwaerdere, S., Callaghan, P. D., Pham, T., L Rahardjo, G. L., Amhaoul, H., Berghofer, P., Quinlivan, M., Mattner, M., Loc’h, C., Katsifis, A., Grégoire, M-C. PET imaging of brain inflammation during early epileptogenesis in a rat model of temporal lobe epilepsy. European Journal of Nuclear Medicine and Molecular Imaging, 2(1) 60 (2012)

 

Denoyer, D., Kirby, L., Waldeck, K., Roselt, P., Neels, O. C., Bourdier, T., Shepherd, R., Katsifis, A., Hicks, R. J. Preclinical characterization of 18FD-FPHCys, a new amino acid-based PET tracer. European Journal of Nuclear Medicine and Molecular Imaging, 39(4) 703-12 (2012)

 

Fraser, B. H., Hamilton, S., Krause-Heuer, A. M., Wright, P., Greguric, I., Tucker, S., Draffan, A., Fokin, V., Sharpless, K. B. Synthesis of 1,4-triazole linked zanamivir dimers as potent inhibitors of influenza. MedChemComm,   (2012)

 

Guastella A. J., Hickie, I. B., McGuinness, M. M., Otis, M., Woods, E. A., Disinger, H. M., Chan, H-K., Chen, T. F., Banati, R. B. Recommendations for the standardisation of oxytocin nasal administration and guidelines for its reporting in human research. Psychoneuroendocrinology,   (2012)

 

Hughes, A. E., Mayo, S., Yang, Y. S., Markley, T., Smith, S. V., Sellaiyan, S., Uedono, A., Hardin, S. G., Muster, T. H. Using X-ray tomography, PALS and Raman spectroscopy for characterization of inhibitors in epoxy coating. Progress in Organic Coatings, 74(4) 726–733 (2012)

 

Kam, W. W. Y., Meikle, S. M., Dunstan, C. R., Banati, R. B. The 18 kDa translocator protein (peripheral benzodiazepine receptor) expression in the bone of normal, osteoprotegerin or low calcium diet treated mice. Public Library of Science, 7(1) e30623 (2012)

 

Krause-Heuer, A. M., Howell, N. R., Matesic, L., Dhand, G., Young, E. L., Burgess, L., Jiang, C. D., Lengkeek, N. A., Fookes, C. J. R., Pham, T. Q., Sobrio, F., Greguric, I., Fraser, B. H. A new class of fluorinated 5-pyrrolidinylsulfonyl isatin caspase inhibitors for PET imaging of apoptosis. Medicinal Chemistry Communications,   (2012)

 

Lehnert, W., Gregoire, M. C., Reilhac, A., Meikle, S. R. Characterization of partial volume effect and region-based correction in small animal Positron Emission Tomography (PET) of the rat brain. NeuroImage, 60(4) 2144–2157 (2012)

 

Lehnert, W., Gregoire, M.-C., Reilhac, A., Meikle, S.R. Performance of an analytical positron range modelling approach in the context of whole body small animal and clinical PET. IEEE Transactions on Nuclear Science,  4285-4288 (2012)

 

Lehnert, W., Gregoire, M-C., Reilhac, A., Meikle, S.R. Comparative study of partial volume correction methods in small animal positron emission tomography (PET) of the rat brain. IEEE Transactions on Nuclear Science,  3807–3811 (2012)

Mattner, F., Staykova, M., Berghofer, P., Wong, H-J., Fordham, S., Callaghan, P., Jackson, T., Pham, T., Gregoire, M-C., Zahra, D., Rahardjo, G., Linares, D., Katsifis, A. Central nervous system expression and PET imaging of the translocator protein in relapsing-remitting experimental autoimmune encephalomyelitis. Journal of Nuclear Medicine, 54 291-298 (2012)

 

Nguyen, V. H., Verdurand, M., Dedeurwaerdere, S., Wang, H., Zahra, D., Gregoire, M-C., Zavitsanou, K. Increased brain metabolism after acute administration of the synthetic cannabinoid HU210: A small animal PET imaging study with 18F-FDG. Brain Research Bulletin, 87(2-3) 172-179 (2012)

 

Nguyen, V. H., Wang, H., Verdurand, M., Zavitsanou, K. Differential treatment regimen-related effects of HU210 on CB1 and D2-like receptor functionality in the rat basal ganglia. Pharmacology, 89(1-2) 64-73 (2012)

 

Ranson, M., Berghofer, P., Vine, K. L., Greguric, I., Shepherd, R., Katsifis, A. Different radiolabelling methods alter the pharmacokinetic and biodistribution properties of Plasminogen Activator Inhibitor Type 2 (PAI-2) forms. Nuclear Medicine and Biology, 39(6) 833-9 (2012)

 

Reilhac, A., Lehnert, W., Lin, J., Meikle, S. R., Gregoire, M-C. Iterative-based Partial Volume Effects correction with wavelet-based regularization for quantitative PET imaging. IEEE Transactions on Nuclear Science,  3788-3791 (2012)

 

Szabo, A. M., Howell, N. R.,  Pellegrini, P., Greguric I., Katsifis, A. Development and validation of competition binding assays for affinity to the extracellular matrix receptors, αvβ3 and αIIbβ3 Integrin. Analytical Biochemistry, 423(1) 70-77 (2012)

 

Verschuer, J. D., Towson, J., Eberl, S., Katsifis, A., Henderson, D., Lam, P., Wen, L., Loc'h, C., Mattner, F., Thomson, S., Mohamed, A., Fulham, M. J. Radiation dosimetry of the translocator protein ligands [(18)F]PBR111 and [(18)F]PBR102. Nuclear Medicine and Biology, 39(5) 742–753 (2012)

 

Vunckx, K., Atre, A., Baete, K., Reilhac, A., Deroose, C. M., Van Laere, K., Nuyts, J. Evaluation of three MRI-based anatomical priors for quantitative PET brain imaging. IEEE Transactions on Medical Imaging, 31(3) 599-612 (2012)

 

Werry, E. L., Liu, G. J., Lovelace, M. D., Nagarajah, R., Bennett, M. R. Glutamate potentiates lipopolysaccharide-stimulated interleukin-10 release from neonatal rat spinal cord astrocytes. Neuroscience, 207 12-24 (2012)

 

Wimberley, C., Fischer, K., Pilcher, B. J., Gregoire, M-C. Validation of the partial saturation approach for in vivo quantification of striatal dopamine D2 receptors with [11C]raclopride. Journal of Cerebral Blood Flow and Metabolism, 32 S13-S40 (2012)

 


Conference Presentations

 

Baccini, D., Hinckley, S., Wild, G., Banos, C. Gamma irradiation effects in fibre Bragg gratings. 20th Australian Institute of Physics Congress, 9 – 13 December 2012. University of New South Wales, Sydney.

 

Banati, R. The measurement of activated microglia as a bio marker for clinical staging of psychotic illness. 5th Mt Lofty workshop on Frontier Technologies for Nervous System Function & Repair, 30 November – 2 December 2012. Mt Lofty, South Australia.

 

Banati, R., Garrett, R., Howell, N., Lavers, J., Paterson, D., de Jonge, M., Howard, D., Nash, J., Dunstan, C. R. Fluorescence micro-probe investigations of trace metal uptake in bone and feathers. 11th International on Synchrotron Radiation Instrumentation (SRI2012), 9 – 13 July 2012. Centre de Congres, Lyon, France.

 

Bello Lamo, M., Sheppard, L., Davies, J., Banos, C., Sheth, S., Reinhard, M. Study of gamma-irradiation effect on TiO2 photocatalysts. 17th International Conference on Semiconductor Photocatalysis and Solar Energy Conversion (SPASEC-17). 11 – 15 November 2012. Jacksonville, Florida, USA.

 

Boisson, F., David Zahra, D., Hamze, D., Meikle, S. R., Gregoire, M-C., Reilhac, A. Imaging performance of the Inveon SPECT system comparing rat and mouse dedicated single and multi-pinhole collimators. IEEE NSS-MIC 2012, 29th October – 3rd November 2012. Anaheim, California.

 

Boisson, F., Lehnert, W., Zahra, D., Gregoire, M-C., Reilhac, A. Validation of PET-SORTEO Monte Carlo simulations for the geometry of the Inveon PET preclinical scanner. IEEE NSS-MIC 2012, 29th October – 3rd November 2012. Anaheim, California.

 

Boisson, F., Parmar, A., Gregoire, M-C. Towards a 3D dynamic study with the Inveon SPECT. 42nd Annual Scientific Meeting of the Australian and New Zealand Society of Nuclear Medicine (ANZSNM 2012). 27-30 April 2012. Melbourne, Australia.

 

Boisson, F., Zahra, D,. Hamze, H., Meikle, S. R., Gregoire, M-C., Reilhac, A. Imaging performance of the Inveon SPECT system comparing rat and mouse dedicated single and multi-pinhole collimators. 20th Australian Institute of Physics Congress, 9-12 December 2012. UNSW, Sydney.

 

Boisson, F., Zahra, D., Hamze, H., Gregoire, M-C.,  Reilhac, A. Validation of PET-SORTEO Monte Carlo simulations for the geometry of the Inveon PET preclinical scanner. 20th Australian Institute of Physics Congress, 9-12 December 2012. UNSW, Sydney.

 

Boisson, F., Zahra, D., Parmar, A., Gregoire, M-., Meikle, S., Reilhac, A. Mouse imaging capabilities of the Inveon SPECT system using single and multipinhole collimators. World Molecular Imaging Congress 2012. 5 - 8 September 2012. Dublin, Ireland.

 

Boisson, F., Zahra, D., Parmar, A., Meikle, S. R., Gregoire, M-C., Reilhac, A. Imaging performance of the Inveon SPECT system using single and multi-pinhole collimators dedicated to mouse studies. IEEE NSS-MIC 2012, 29th October – 3rd November 2012. Anaheim, California.

 

Davies, J. B., Banos, C. Gamma irradiation in the manufacture and sterilisation of musculoskeletal allograft tissue. 13th Australasian Tissue and Biotherapeutics Forum (ATBF), 14th lnternational Asia Pacific Association of Surgical Tissue Banking (APASTB)


Fischer, K., Wimberley, C., Nguyen, H., Gregoire, M-C., Pichler, B. J. In vivo quantification of striatal dopamine D2 receptor expression and [11C]Raclopride affinity using a single injection protocol. 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM12). 9th-11th August, 2012. Baltimore, USA.

 

Hinckley, S., Low-cost educational optical coherence tomography system for thickness measurements. 20th Australian Institute of Physics Congress, 9 – 13 December 2012. University of New South Wales, Sydney.

 

Ho Shon, I. A., Kumar, D., Sathikumar, C.,  Som, S.,  Berghofer, P.,  Van, K., Chicco, A., Park, D.,  Dyszlewski, M.,  Hogg, P. J. Comparison of a novel Hsp90 ligand radiolabelled with Indium-111 and Gallium-67 for imaging of cell death and dosimetry estimations. 25th Annual European Association of Nuclear Medicine (EANM)

 

Howell, N., Lavers, J., Uematsu, S., Garrett, R., de Jonge, M., Patterson, D., Howard, D., Banati, R. Fluorescence micro-probe investigations of elemental distribution in feathers. 2012 Australian Synchrotron User Meeting, 29 - 30 November 2012. Melbourne, Australia.

 

Hutton, B. F., Thomas, B., Erlandsson, K., Bousse, A., Kazantsev, D., Pdedmonte, S., Arridge, S., Ourselin, S., Reilhac, A. What approach to brain partial volume correction is best for PET/MRI? PET/MR and SPECT/MR: New Paradigms for Combined Modalities in Molecular Imaging Conference (PSMR 2012), 26 – 30 May, 2012. La Biodola, Isola d'Elba, Italy.

 

Kam, WWY; McNamara, A; Davies, JB; Banati RB The response of messenger RNA to ionizing radiation – mitochondrial genes are more susceptible. International Conference on Translational Research in Radio-Oncology and Physics for Health in Europe (ICTR-PHE), 27 Feb - 2 Mar, 2012, Geneva.

 

Krause-Heuer, A. M., Howell, N. R., Matesic, L., Young, E., Burgess, L., Dhand, G., Greguric, I., Fraser, B. H. Potent caspase inhibitors for apoptotic disease imaging. 19th International Conference on Organic Synthesis (ICOS-19), 1st - 6th July 2012. Melbourne, Australia.

 

Matesic, L., Wyatt, N. A., Fraser, B. H., Grant, M., Pham, T. Q., Greguric, I. Microfluidics as an emerging technology for the synthesis of PET imaging agents. 42nd Annual Scientific Meeting of the Australian and New Zealand Society of Nuclear Medicine (ANZSNM 2012). 27-30 April 2012. Melbourne, Australia.

 

Matesic, L., Wyatt, N. A., Fraser, B. H., Pham, T. Q., Greguric, I. Rapid synthesis of [18F]sulfonyl fluoride groups using microfluidics. 19th International Conference on Organic Synthesis (ICOS-19), 1st - 6th July 2012. Melbourne, Australia.

 

Mume, E., Uedono, A., Mizunaga, G., Smith, S. V. Nuclear sensors and positron annihilation lifetime spectroscopy for characterising nanoscale mesoporous silica. Colloids and Nanomedicine 2012, 15-17 July 2012. Amsterdam, the Netherlands.

 

Parmar, A., Allen, J., Boisson, F., Gregoire, M-C., Clarke, S., Katsifis, A., Robertson, G. R. Imaging altered drug clearance in colon cancer xenograft model using (99m)Tc-Sestamibi. World Molecular Imaging Congress 2012. 5 - 8 September 2012. Dublin, Ireland.

 

Parmar, A., Boisson, F., Katsifis, A., Robertson, G., Allen, J., Gregoire, M-C. In vivo imaging of 99mTc-Sestamibi in mice for predicting drug clearance and toxicity. 42nd Annual Scientific Meeting of the Australian and New Zealand Society of Nuclear Medicine (ANZSNM 2012). 27-30 April 2012. Melbourne, Australia.

 

Patterson, H Adapting delivery of education and training to suit multi-disciplinary requirements. 10th Asia Oceania Federation of Nuclear Medicine and Biology, May 2012. Iran.

 

Prokopovich, D. A., Boardman, D.,  Kyme, A. Z., Angelis, G., Boisson, F., Reinhard, M. I., Meikle, S. R. Design and characterisation of a detector for imaging 1-25I emissions from freely moving mice. IEEE NSS-MIC 2012, 29th October – 3rd November 2012. Anaheim, California.

 

Reilhac, A., Angelis, G., Wimberley, C., Boisson, F., Meikle, S. R., Gregoire, M-C. 4D PET iterative deconvolution in wavelet space with basis function-based regularization for quantitative dynamic PET imaging. IEEE NSS-MIC 2012, 29th October – 3rd November 2012. Anaheim, California.

 

Siegele, R., Howell, N., Callaghan, P. D., Cohen, D. D. Investigation of elemental changes in brain tissues following excitotoxic injury. 13th International Conference on Nuclear Microprobe Technology & Applications 2012 (ICNMTA2012). 22 - 27 July 2012. Lisbon, Spain.

 

Thomas, B. A., Erlandsson, L., Reilhac, A., Bousse, A., Kazantsev, D., Pedemonte, S,. Vunckx, K., Arridge, S., Ourselin, S., Hutton, B. A comparison of the options for brain partial volume correction using PET/MRI. IEEE NSS-MIC 2012, 29th October – 3rd November 2012. Anaheim, California.

 

Vasilescu, I. M., Mume, E., Smith, S. V. Radiometal complexation of macrocyclic ligands, kinetic and competitive studies. 40 International Conference on Coordination Chemistry, (ICCC40), 9th – 13th September, 2012. Valencia, Spain.

 

Verdurand, M., Fillman, S., Shannon Weickert, C., Zavitsanou, K. Parallel increases in [3H]Muscimol and [3H]Flumazenil binding in the dorsolateral prefrontal cortex in schizophrenia are linked to GABAA receptor α4 and γ2S . 3rd Schizophrenia International Research Conference. April, 2012.

 

Ware, R. E., Kee, D., McArthur, G. A., Brglevska, S., Callahan, J., Roselt, P., Neels, O. C., Drummond, E., Greguric, I., Boudier, T., Katsifis, A., Hicks, R. J. First-time-in-human study of N-(2-(diethylamino)ethyl)-6-[F-18]fluoropyridine-3-carboxamide (MEL050). 16th European Symposium on Radiopharmacy and Radiopharmaceuticals (ESRR’12). 26th-29th April 2012. Nantes, France.

 

Wichmann, C. W., Haskali, M., Noonan, W., Bourdier, T., Pham, T., Wyatt, N., Grant, M., Greguric, I., Katsifis, A., Poniger, S., Hicks, R., Roselt, P. Preparation of versatile radiolabeled prosthetic groups and their application using a newly designed automated dual reactor device. 16th European Symposium on Radiopharmacy and Radiopharmaceuticals (ESRR’12). 26 – 29 April 2012. Nantes, France.

 

Wimberley, C., Fischer, K., Pilcher, B. J., Gregoire, M-C. Validation of the partial saturation approach for in vivo quantification of striatal dopamine D2 receptors with [11C]Raclopride. 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM12). 9th-11th August, 2012. Baltimore, USA.