Dr Natalia Davydova

Molecular Biologist - Biodeuteration
Phone - +61 2 9717 9526
   
Natalia Davydova staff profile

Profile

Role at ANSTO
 
Natalia is a Molecular biologist at the National Deuteration Facility (NDF). She is responsible for the molecular cloning of different protein constructs used for biodeuteration. Before joining ANSTO in 2014 she was involved in multiple international projects on Structural biology of ribosome and Cancer research. 
Expertise
 
Molecular cloning and site-directed mutagenesis, protein isolation and characterization, protein crystallography
 
 

Selected publications

Kuter, D., Streltsov, V., Davydova, N., Venter, G.A., Naidoo, K.J., Egan, T.J. (2014): Molecular Structures and Solvation of Free Monomeric and Dimeric Ferriheme in Aqueous Solution: Insights from Molecular Dynamics Simulations and Extended X-ray Absorption Fine Structure Spectroscopy. Inorg. Chem., 53, 10811-10824.
 
Nisbet, R.M., Nuttall, S.D., Robert, R., Caine, J.M., Dolezal, O., Hattarki, M., Pearce, L.A., Davydova, N., Masters, C.L., Varghese, J.N., Streltsov, V.A. (2013): Structural studies of the tethered N-terminus of the Alzheimer’s disease amyloid-β peptide. Proteins, 81, 1748-1758.
 
Harris, N.C., Davydova, N., Roufail, S., Paquet-Fifield, S., Paavonen, K., Karnezis, T., Zhang, Y-F., Sato, T., Rothacker J., Nice E.C., Stacker, S.A., Achen, M. G. (2013): The propeptides of VEGF-D determine heparin binding, receptor heterodimerization and effects on tumor biology. J. Biol. Chem., 288, 8176-8186.
 
Davydova, N., Streltsov, V.A., Roufail, S., Lovrecz, G.O., Stacker, S.A., Adams, T.E., Achen, M.G. (2012): Preparation of human vascular endothelial growth factor-D for structural and preclinical therapeutic studies. Protein Expr. Purif., 82, 232-239.
 
Davydova, N., Roufail, S., Streltsov, V.A., Stacker, S.A., Achen, M. G. (2011): The VD1 neutralizing antibody to Vascular Endothelial Growth Factor-D: binding epitope and relationship to receptor binding. J. Mol. Biol., 407, 581-593.
 
Nikulin, A., Eliseikina, I., Tishchenko, S., Nevskaya, N., Davydova, N., Platonova, O., Piendl, W., Selmer, M., Liljas, A., Drygin, D., Zimmermann, R., Garber, M. and Nikonov, S. (2003): Structure of the L1 protuberance in the ribosome. Nature Structural Biology 10, 104-108.
 
Simpson, P.J., Davydova, N., Curry, S. and Matthews, S. (2002): Resonance assignment and topology of the 2H, 13C, 15N labelled 29 kDa N-terminal fragment of the polypyrimidine tract binding protein (PTB). Journal of Biomolecular NMR 24, 79-80.
 
Davydova, N., Streltsov, V., Wilce, M., Liljas, A. and Garber, M. (2002): L22 ribosomal protein and effect of its mutation on ribosome resistance to erythromycin. Journal of Molecular Biology 322, 635-644. 
 
Helgstrand, M., Rak, A.V., Allard, P., Davydova, N., Garber, M.B. and Härd, T. (1999): Solution structure of the ribosomal protein S19 from Thermus thermophilus. Journal of Molecular Biology 292, 1071-1081.
 
Unge, J., Åberg, A., Al-Karadaghi, S., Nikulin, A., Nikonov, S., Davydova, N., Nevskaya, N., Garber, M. and Liljas, A. (1998): The crystal structure of ribosomal protein L22 from Thermus thermophilus: insights into the mechanism of erythromycin resistance. Structure 6, 1577-1586.
 
Davydova, N.L., Rak, A.V., Gryaznova, O.I., Liljas, A., Jonsson, B. -H., Berglund, H., Härd, T. and Garber, M. B. (1997): Preliminary NMR studies of Thermus thermophilus ribosomal protein S19 overproduced in Escherihia coli. FEBS Letters 415, 155-159.