Dr Maxine Roberts

Radiochemist
Phone - +61 2 9717 9894
   
ROBERTS_Maxine staff photo

Profile

 

Role at ANSTO

 

Maxine's responsibilities include carrying out synthetic and radiochemistry research activities for ANSTO LifeSciences, the CRC Biomedical Imaging Development collaboration and associated collaborators. She focuses on the development of labelled radiotracers for PET and SPECT imaging.


Background


Maxine first joined ANSTO in 2010 as a post-doctoral research fellow for the CRC Biomedical Imaging Development collaboration before accepting a radiochemist position in 2012 in ANSTO LifeSciences. Maxine contributes to both the synthetic and radiochemistry aspects of ANSTO LifeSciences and other collaborative projects.


Research interests and areas of expertise

 

Maxine has expertise in radiochemistry, particularly 18F manual & automated radiolabelling and radiometabolite animal studies, in addition other radioisotopes such as 123I and 125I. Maxine also has expertise in organic and medicinal chemistry.


Qualifications & Achievements

 

  • PhD in synthetic chemistry, the University of Western Sydney, 2012.
  • Bachelor of Medical Science (Hons), Class 1, the University of Western Sydney, 2006.
  • Bachelor of Medical Science, the University of Western Sydney, 2005.
  • Maxine is a member of the Women in Nuclear association.

 

 

Selected publications

Roberts, M. P., Nguyen, V., Ashford, M. E., Berghofer, P., Wyatt, N. A., Krause-Heuer, A. M., Pham, T. Q., Taylor, S. R., Hogan, L., Jiang, C. D., Fraser, B. H., Lengkeek, N. A., Matesic, L., Gregoire, M. C., Denoyer, D., Hicks, R. J and Greguric, I. Synthesis and in vivo evaluation of [123I]melanin-targeted agents. Journal of Medicinal Chemistry, 58(15), 6214-6224 (2015). doi: 10.1021/acs.jmedchem.5b00777


Roberts, M. P., Pham, T. Q., Doan, J., Jiang, C. D., Hambley, T. W., Greguric, I., Fraser, B. H. Radiosynthesis and ‘click’ conjugation of ethynyl-4-[18F]fluorobenzene - an improved [18F]synthon for indirect radiolabeling. Journal of Labelled Compounds and Radiopharmaceuticals, 58(13-14), 473-478 (2015). doi: 10.1002/jlcr.3354


Matesic, L., Wyatt, N. A., Fraser, B. H., Roberts, M. P., Pham, T. Q., Greguric, I. Ascertaining the suitability of aryl sulfonyl fluorides for [18F]radiochemistry applications: a systematic investigation using microfluidics. Journal of Organic Chemistry, 78(22), 11262-11270 (2013). doi: 10.1021/jo401759z


Taylor, S. R., Roberts, M. P., Wyatt, N. A., Pham, T. Q., Stark, D., Bourdier, T., Roselt, P., Katsifis, A., Greguric, I. Synthesis and radiosynthesis of a novel PET fluorobenzyl piperazine for melanoma tumour imaging; [18F]MEL054. Australian Journal of Chemistry, 66 (4), 491-499 (2013). doi: 10.1071/CH12489


Garbutcheon-Singh, K. B., Grant, M. P., Harper, B. W., Krause-Heuer, A. M., Manohar, M., Orkey, N. U, Aldrich Wright, J. R. Transition metal based anticancer drugs. Current topics in Medicinal Chemistry, 11, 521-542. (2011

 

Van Holst, M., Grant, M. P., Aldrich-Wright, J. R. Target biological structures in the cell, organelles, DNA and RNA. In J. Aldrich-Wright (Ed.), Metallointercalators, Synthesis and Techniques to Probe their Interactions with Biomolecules (chapter 1). ISBN 978-3-211-09427-3. (2011)


Harper, B. W., Krause-Heuer, A. M., Grant, M. P., Manohar, M., Garbutcheon-Singh, K. B., Aldrich Wright, J. R. Advances in platinum chemotherapeutics. Chemistry - A European Journal, 16(24), 7064-7077. (2010)


Grant, M. P., Wheate, N. J., Aldrich-Wright, J. R. Diffusion coefficient of cucurbit[n]urils (n = 6 or 7) at various concentrations, temperatures and pH. Journal of Chemical & Engineering Data, 54(2), 323-326. (2009)


Krause-Heuer, A. M., Grant, M. P., Orkey, N., Aldrich-Wright, J. R. Drug delivery devices and targeting agents for platinum(II) anticancer complexes. Australian Journal of Chemistry, 61(9), 675-681. (2008)