Dr Anna Sokolova
Role at ANSTO
Dr Anna Sokolova is a Project Leader for the design, construction and commissioning of BILBY, the new time-of-flight small-angle neutron scattering instrument at the Bragg Institute.
Anna Sokolova is a physicist from Institute of Crystallography, Russian Academy of Sciences (RAS), Small Angle Scattering Laboratory. During her PhD and the following several years, she extensively worked in the European Molecular Biology Laboratory (EMBL, Hamburg outstation c/o Deutsche Electronen Synchrotron).
She has a Masters in Physics/Biophysics from Faculty of Physics, M.V.Lomonosov Moscow State University, and a PhD in Condensed Matter Physics at the Institute of Crystallography RAS (Moscow, Russia). Both were focused on development of new methods for small angle scattering data analysis and interpretation as well as on SAXS technique implementation to proteins structure studies.
From 2007 to 2009 Anna worked as a Postdoctoral Fellow in Food Science Project Group at the Bragg Institute, ANSTO.
Anna’s main scientific interest is the complex biology related structures small angle scattering data collection, processing and interpretation. She also practised at the Institute of Bioorganic Chemistry RAS (Moscow, Russia) in basic biochemistry technics for protein sample preparation. Along with that, her interest and experience expanded significantly into the area of design, building and testing of SANS instrumentation, as well as into the field of setting up and adopting SANS machines for wide type of experiments. Also Anna has experience in programming (Fortran; HTML and PHP for web-applications development, Python) and mathematical methods in structural research.
Qualifications & Achievements
Academia Europea Prize for young scientist in physics
PhD defended in the field of physics and mathematics.
First diploma in contest of scientific works of young scientists in the Institue of Crystallography RAS
MSc in physics (diploma cum laude and the golden medal for excellent graduation), Faculty of Physics, Chair of Biophysics, M.V.Lomonosov Moscow State University
2016-2019: Member of the Scientific and Technical Advisory Panel for Small Angle Neutron Scattering for the European Spallation Source.
1994 - 2000: Faculty of Physics, M.V. Lomonosov Moscow State University, Moscow, Russia
2000-2004: PhD, Institute of Crystallography, Russian Academy of Sciences, Moscow, Russia
Sokolova A.; Christoforidis J.; Eltobaji A.; Barnes J.; Darmann F.; Whitten A.E.; de Campo L. BILBY: Time-of-Flight Small Angle Scattering Instrument Neutron News, 2016, 27(2): 9-13
Wood K.; Jeffries C.M.; Knott R.B.; Sokolova A.V.; Jacques D.A.; Duff A.P. Exploring the structure of biological macromolecules in solution using Quokka, the small angle neutron scattering instrument, at ANSTO Nuclear instruments & methods in physics research, Section A - Accelerators Spectrometers Detectors and Associated Equipment, 2015, 798: 44-51
Kikhney A.G.; Panjkovich A.; Sokolova A.; Svergun D.I. DARA: a web server for rapid search pf structural neighbours using solution small angle X-ray scattering data. Bioinformatics, 2015, 32(4): 616-618
Pham C.L.L.; Kirby N.; Wood K.; Ryan T.; Roberts B.; Sokolova A.V.; Barnham K.J.; Masters C.L.; Knott R.B.; Cappai R.; Curtain C.C.; Rekas A. Guanidine hydrochloride denaturation of dopamine-induced alpha-synuclein oligomers: A small-angle X-ray scattering study. PROTEINS: Structure, Function and Bioinformatics, 2014, 82(1): 10-21
Jiang L.; Phang J.M.; Yu J.; Harrop S.J.; Sokolova A.V.; Duff A.P.; Wilk K.E.; Alkhamici H.; Breit S.N.; Valenzuela S.M.; Brown L.J.l Curmi P.M. CLIC protein, ezrin, radixin, moesin and the copuling of membranes to the actic cytoskeletons: A smoking gun? Biochim Biophys Acta, 2014. February, 1838 (2): 643-657
Sokolova A.V.; Huang S.-L.; Duff A.; Gilbert E.P.; Li W.-H. Correlation of thermostability and confirmational changes of catechol 2,3-dioxygenases from two disparate micro-organisms, Biophysical Chemistry, 2013, 180-181: 145-152
Kealley C.; Sokolova A. V.; Kearley G. J.; Kemner E.; Russina M.; Faraone A.; Hamilton W. A.; Gilbert E. P. Dynamical transition in a large globular protein: macroscopic properties and glass transition, Biochimica et Biophysica Acta - Proteins and Proteomics. 2010. January, 1804(1): 34-40
Rekas A.; Knott R.; Sokolova A.V.; Barnham K.J.; Perez K.A.; Masters C.L.; Drew S.C.; Cappai R.; Curtain C.C.; Pham C.L.L. The structure of dopamine induced alpha-synuclein oligomer, European Biophysical Journal, 2010, 39(10):1407-1419
Sokolova A. V., Kreplak L, Svergun D. I., Wedig T., Herrmann H., Aebi U., and Strelkov S. V. Monitoring intermediate filament assembly by small-angle x-ray scattering reveals the molecular architecture of assembly intermediates, PNAS October 31, 2006. 103 no. 44: 16206-16211
Konarev P. V., Volkov V. V., Sokolova A. V., Koch M. H. J. and Svergun D. I. PRIMUS: a Windows PC-based system for small-angle scattering data analysis, J.Appl.Cryst. 2003. 36: 1277-1282
Sokolova A. V., Malfois M., Caldentey J., Svergun D. I., Koch M. H. J., Bamford D. H. and Tuma R. Solution structure of bacteriophage PRD1 vertex complex, J. Biol.Chem. 2001, 49, Issue of December, 276: 46187-46195