Dr Gary Perkins

Radiochemistry development platform Co-ordinator
Phone - +61 2 9565 7632
   
Perkins Gary

Profile

 

Role at ANSTO

 

Gary Perkins is ANSTO’s Radiochemistry Development Platform Coordinator and the National Imaging Facility Fellow at the University of Sydney/ANSTO node.

 

Gary started at ANSTO looking at the development of several treatment and diagnosis based drugs such as 195mPt-cisplatium. In 2010 Gary travelled to South Africa to conduct a technology transfer which resulted in a Phase Zero Clinical trial of 195mPt-cisplatium. Since then Gary has continued in the radiochemistry field investigating new production methods for new and known radiotracers particularly focused of 18F and 11C. He is currently the lead production person at ANSTO with skills in vessel-based and microfluidic automated systems.

 

Not just focused on traditional uses of 11C Gary is also interested in new uses such as monitoring the effect of greenhouse gases (carbon dioxide) in plants. Gary manages a Physical Containment Level 2 Plant Facility at ANSTO which aims to investigate the interactions between plants (potentially genetically modified) and environmental gases.

 

Along with this he also has skills in custom irradiations using the IBA 18MeV cyclotron, including maintenance of specific components such as targets and ion sources.

 

Gary also leads RADSET (Research and Development of Scientific Equipment Team), which looks at building unique automated solutions to significant problems in the radiochemistry field. As part of this team Gary offers skills in 3D and engineering modelling, software and electronic developments. In 2017 the team’s automated cleaning system gained international recognition with Synthra CEO commenting that ANSTO showed the clear “advantages of an automated cleaning system”.

 

Gary’s main interests now lie in the development of new automated systems that can improve consistency and reduce operator dose throughout the whole radiochemistry cycle.
 


Qualifications & Achievements

 

PhD in organometallics in 2006 looking at a model for molecular wires under the supervision of Prof Michael Bruce.
BSc (Hons) the University of Adelaide.


 

 

 

Selected publications

Perkins, G., Sheth, R., Greguric, I., Pascali, G. Optimization of [11C]-Raclopride production using a Synthra GPextent system. Current Radiopharmaceuticals, 7(2), 100-6 (2014). doi: 10.2174/1874471007666141021111635

 

Boisson, F., Wimberley, C., Lehnert, W., Zahra, D., Pham, T., Perkins, G., Hamze, H., Gregoire, M-C., Reilhac, A. NEMA NU 4-2008 Validation and applications of the PET-SORTEO Monte Carlo simulations platform for the geometry of the Inveon PET preclinical scanner. Physics in Medicine and Biology, 58(19), 6749-6763 (2013). doi: 10.1088/0031-9155/58/19/6749

 

Zeevaart, J. R., Wagener, J., Marjanovic-Painter, B., Sathekge, M., Soni, N., Zinn, C., Perkins, G., Smith, S. V. Production of high specific activity Pt-195m-cisplatinum at South African Nuclear Energy Corporation for Phase 0 clinical trials in healthy individual subjects. Journal of Labelled Compounds and Radiopharmaceuticals, 56(9-10) SI, 495-503 (2013). doi: 10.1002/jlcr.3091

 

Bruce, M. I., Costuas, K., Davin, T., Halet, J-F., Kramarczuk, K. A., Low, P. J., Nicholson, B. K., Perkins, G. J., Roberts, R. L., Skelton, B. W., White, A. H. Syntheses, structures and redox properties of some complexes containing the Os(dppe)Cp* fragment, including [{Os(dppe)Cp*}2(m-C=CC=C)]. Dalton Transactions, 46, 5387-5399. (2007)

 

Bruce, M. I., Costuas, K., Ellis, B. G., Halet, J-F., Low, P. J., Moubaraki, B., Murray, K. S., Ouddai, N., Perkins, G. J., Skelton, B. W., White, A. H. Redox-active complexes containing Group 8 metal centres linked by C2 bridges. Organometallics, 26(15), 3735-3745. (2007)

 

Bruce, M. I., Humphrey, P. A., Jevric, M., Perkins, G. J., Skelton, B. W., White, A. H. Heterometallic complexes containing 1,1(C=C)2Fc units linking two different metal centres. Journal of Organometallic Chemistry, 692, 1748-1756. (2007;

 

Bruce, M. I., Jevric, M., Perkins, G. J., Skelton, B. W., White, A. H. Trimetallic complexes containing 1-1-Rc(C=C)2 [Rc = rutheocene-1,1-diyl, Ru(-C5H4-)2]. Journal of Organometallic Chemistry, 692, 1757-1765. (2007)

 

Perkins, G. J., Bruce, M. I., Skelton, B. W., White, A. H. A new precursor for organo-osmium complexes. Inorganica Chimica Acta, 359, 2644-2649. (2006)

 

Bruce, M. I., Low, P. J., Frantisek, H., Humphrey, P. A., De Montigny, F., Jevric, M., Lapinte, C., Perkins, G. J., Roberts, R. L., Skelton, B. W., White, A. H. Synthesis, structure, some reactions, and electrochemical oxidation of ferrocenylethynyl complexes of iron, ruthenium, and osmium. Organometallics, 24(22), 5241-5255. (2005)

 

Bruce, M. I., Kramarczuk, K. A., Perkins, G. J., Skelton, B. W., White, A. H. Synthesis and crystal structures of some CCo3 clusters containing PPh3 or dppm ligands. Journal of Cluster Science, 15(2), 119-137. (2004)

 

Antonova, A. B., Bruce, M. I., Ellis, B. G., Gaudio, M., Humphrey, P. A., Jevric, M. Melino, G., Nicholson, B. K., Perkins, G. J., Skelton, B. W., Stapleton, B., White, A. H., Zaitseva, N. N. A novel methodology for the synthesis of complexes containing long carbon chains linking metal centres: molecular structures of {Ru(dppe)Cp*}2(m-C14) and {Co3(m-dppm)(CO)7}2(m3:m3-C16). Chemical Communications, 8, 960-961. (2004)