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Nigel Lengkeek

Dr Nigel Lengkeek

Radiometals Team Leader / Organic Chemist

Role at ANSTO

Nigel leads the radiometals theme within radiochemistry covering projects exploring radioisotope generators, radiochemical separations, novel ligand design for radiometals such as 64Cu, 68Ga, 89Zr and 177Lu, radiometal labelling of small molecules through to particles, and novel bio-conjugation strategies.

Background

After completing his PhD in Chemistry in 2007 at the University of Western Australia under the supervision of Prof. George Koutsantonis and Prof. Jack Harrowfield, Nigel remained at UWA until June 2010 working as a postdoctoral research associate in the Chemistry and Pharmacy Disciplines.

Nigel joined ANSTO in July 2010 as a Postdoctoral Research Fellow supported by the CRC for Biomedical Imaging Development. In June 2011 he moved to the role of organic chemist in ANSTO Lifesciences and has continued to develop the radiochemistry capability in radiometal research.

Research interests and areas of expertise

Nigel’s research interests lie in rational radiometal ligand development, novel bioconjugation methods, production and separation of PET and therapeutic radionuclides, and use medical and industrial use of radiometals. He has expertise in synthetic inorganic and organic chemistry, radiochemistry and a proficiency in a broad range of physical characterisation and separation techniques, including multinuclear NMR, UV-Vis-NIR, IR and fluorescence spectroscopy, analytical and preparative HPLC, SEC/GPC, GC, GC-MS, electrochemistry, ion-exchange and size-exclusion chromatography.

Nigel maintains collaborative research ties with researchers at University of Sydney and the University of New South Wales. He co-supervises a PhD student.

Nigel’s key international collaborators in the area of radiometals include Prof Jason Lewis and A/Prof Kishore Pillarsetty at the Memorial Sloan Kettering Cancer Centre in New York.

Qualifications & Achievements

PhD (Chem) from the University of Western Australia (2007)BSc (Chem) / BE (Materials) from the University of Western Australia (2002)

During his PhD, Nigel was awarded the Alexander Cohen Postgraduate travel award to work in the laboratories of Prof. Jean-Pierre Sauvage at Université Strasbourg (formally Université Louis Pasteur) for three months.

Nigel is a member of the Royal Australian Chemical Society (MRACI CCHEM), the American Chemical Society the Australian and New Zealand Society of Nuclear Medicine. He currently serves as the Treasurer for the RACI Radiochemistry Division.