Skip to main content
Chemistry instrument lab

Deuteration Publications

Updated by NDF staff 18/04/2023


  1. DGet! An open source deuteration calculator for mass spectrometry data.
    Lockwood, T.E., Angeloski, A.
    J Cheminform, 2024, 16(36). 
  2. Probing the binding sites of bioactives with β-Lactoglobulin at different gastrointestinal pHs.
    Ghosh, S., Melton, L. D., Kihara, S., Huang, R., Leung, I. K. H., Rekas, A., Knott, R., Seal, C., Nieuwoudt, M., McGillivray, D. J.
    Food Hydrocolloids, 2024, 153, 110040.
  3. Ab initio-based determination of lanthanoid–radical exchange as visualised by inelastic neutron scattering.
    Dunstan, M. A., Giansiracusa, M. J., Calvello, S., Sorace, L., Krause-Heuer, A. M., Soncini, A., Mole, R. A., Boskovic, C.
    Chemical Science, 2024,15, 4466-4477
  4. Small-Angle Neutron Scattering Insights into 2-Ethylhexyl Laurate: A Remarkable Bioester.
    Hammond, O. S., Morris, D. C., Bousrez, G., Li, S., de Campo, L., Recsei, C., Moir, M., Glavatskih, S., Rutland, M. W., Mudring, A.
    ACS Sustainable Chem. Eng. 2024, 12, 5, 1816–1821.
  5. Structure of biomimetic casein micelles: Critical tests of the hydrophobic colloid and multivalent-binding models using recombinant deuterated and phosphorylated β-casein.
    Raynes, J. K., Mata, J., Wilde, K. L., Carver, J. A., Kelly, S. M., Holt, C.
    Journal of Structural Biology, 2024, 9,100096.
  6. Evolution of the structure of lipid nanoparticles for nucleic acid delivery: From in situ studies of formulation to colloidal stability.
    Gilbert, J., Sebastiani, F., Yanez Arteta, M.,Terry, A., Fornell, A., Russell, R., Mahmoudi, N., Nylander, T.
    Journal of Colloid and Interface Science, 2024, 660, 66-76.


  1. pH-dependent interactions of coacervate-forming histidine-rich peptide with model lipid membranes.
    Gudlur, S., Ferreira, F. V., Ting, J., Domene, C., Maricar, S., Le Brun, A. P., Yepuri, N., Moir, M., Russell, R., Darwish, T., Miserez, A., Cárdenas, M.
    Front. Soft Matter, 2023 (3).
  2. Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake.
    Ferrari, A., Whang, E., Xiao X., Kennelly, J. P., Romartinez-Alonso, B., Mack, J. M., Weston, T., Chen, K., Kim, Y., Tol, M. J., Bideyan, L., Nguyen, A., Gao, Y., Cui, L., Bedard, A. H., Sandhu, J., Lee, S, D., Fairall, L., Williams, K. J., Song, W., Munguia, P., Russell, R. A., Martin,, M. G., Jung, M. E., Jiang, H., Schwabe, J. R. W., Young S. G., Tontonoz, P.
    Science 2023, 382 (6671).
  3. Triglyceride-Tethered Membrane Lipase Sensor.
    Lankage, U., Holt, S. A., Bridge, S., Cornell, B., Cranfield, C. G.
    ACS Applied Material Interfaces 2023.
  4. Measuring The Interactions and Influence of Amphipathic Copolymers with Lipid Monolayers and Bilayers as Models of Biological Membranes.
    Frost, C., Wiedbrauk, S., Graham, E., Yepuri, N R., Nelson, A. R. J., Boase, N. R. B.
    Macromolecular Chemistry and Physics 2023.
  5. Terminal Deuterium Atoms Protect Silicon from Oxidation.
    Li, T., Peiris, C, R.,  Aragonès, A. C., Hurtado, C., Kicic, A., Ciampi, S., MacGregor, M., Darwish, T., Darwish, N.
    ACS Applied Material Interfaces 2023, 15, 40, 47833–47844.
  6. Deuterated squalene and sterols from modified Saccharomyces cerevisiae
    Recsei, C., Russell, R. A., Cagnes, M., Darwish, T.
    Organic & Biomolecular Chemistry 2023, 21, 6537-6548.
  7. Highly anisotropic magnetoresistance of organic light-emitting diodes at geomagnetic field strengths.
    Grünbaum, T., Mkhitaryan, V. V., Schmid, E., Dallinger, F., Bange, S., Jiang, W., Darwish, T. A., Burn, P. L., Lupton, J. M.
    Physical Review B 2023, 108, 035201.
  8. Binding and Dynamics Demonstrate the Destabilization of Ligand Binding for the S688Y Mutation in the NMDA Receptor GluN1 Subunit.
    Chen, J. Z., Church, W. B., Bastard, K., Duff, A.P., Balle, T.
    Molecules 2023, 28, 4108.
  9. High-Density Lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner.

    Correa, Y., Del Giudice, R., Waldie, S., Thépaut, M., Micciula, S., Gerelli, Y., Moulin, M., Delaunay, C., Fieschi, F., Pichler, H., Haertlein, M., Forsyth, V. T., Le Brun, A., Moir, M., Russell, R. A., Darwish, T., Brinck, J., Wodaje, T., Jansen, M., Martín, C., Roosen-Runge, F., Cárdenas, M.
    Journal of Colloid and Interface Science 2023, 645, 627-638

  10. Effect of Cholesterol on Biomimetic Membrane Curvature and Coronavirus Fusion Peptide Encapsulation.

    Milogrodzka, I., Nguyen,  P., Sama, G., Samadian, H., Zhai, J., de Campo, L., Kirby, N., Scott, T., Banaszak Holl, M.
    ACS Nano 2023, 17, 9, 8598–8612.

  11. NMR characterization of an assembling RHIM (RIP homotypic interaction motif) amyloid reveals a cryptic region for self-recognition.
    Pham, C., Titaux-Delgado, G., Varghese, N., Polonio, P., Wilde, K., Sunde, M., Mompeán, M.
    Journal of Biological Chemistry 299 (4) 104568.
  12. Sterol Structural Features’ Impact on the Spontaneous Membrane Insertion of CLIC1 into Artificial Lipid Membranes.
    Hossain, K., Turkewitz, D., Holt, S., Le Brun, A., Valenzuela, S.
    Langmuir 2023, 39, 9, 3286–3300.
  13. Structural basis underlying the synergism of NADase and SLO during group A Streptococcus infection.

    Tsai, W-J., Lai, Y-H., Shi, Y-A., Hammel, M., Duff, A., Whitten, A., Wilde, K., Wu, C-M., Knott, R., Jeng, U. Kang, C-Y., Hsu, C-Y., Wu, J-L., Tsai, P-J., Chiang-Ni, C., Wu, J-J., Lin, Y-S., Liu, C-C., Senda, T., Wang, S.
    Commun Biol 6, 124 (2023).

  14. Inelastic Neutron Scattering Measurement of the Ground State Tunneling Gap in Tb and Ho Analogues of a Dy Field-Induced Single-Molecule Magnet.
    Atkin, A., Giansiracusa, M., Calvello, S., Rousset, E., Gable, R., Phonsri, W., Murray, K., Howard, J., Soncini, A., Mole, R., Boskovic, C.
    Inorganic Chemistry, 2023, 62, 3, 1141–1155
  15. Investigation on the relationship between lipid composition and structure in model membranes composed of extracted natural phospholipids.
    Santamaria, A., Batchu, K., Fragneto, G., Laux, V., Haertlein, M., Darwish, T., Russell, R., Zaccai, N., Guzmán, E., Maestro, A.
    Journal of Colloid and Interface Science, 637, 55-66.
  16. Structural Characterization of Nanoparticle-Supported Lipid Bilayer Arrays by Grazing Incidence X-ray and Neutron Scattering.

    Paracini, N., Gutfreund, P., Welbourn, R., Gonzalez-Martinez, J., Zhu, K., M., Yansong., Yepuri, N., Darwish T., Garvey, C., Waldie, S., Larsson, J., Wolff, M., Cárdenas, M.
    ACS Applied Material Interfaces 2023, 15, 3, 3772–3780.


  1. Crowder-directed interactions and conformational dynamics in multistimuli-responsive intrinsically disordered protein.
    Balu, R., Wanasingha, N., Mata, J., Rekas, A., Barrett, S., Thornton, G., Hill, A., Choudhury, N., Dutta, N.
    Science Advances, 8(51).
  2. Tribotronic control of an ionic boundary layer in operando extends the limits of lubrication.
    Bhaskar Reddy, A., Pilkington, G., Rutland, A., Glavatskih, S.
    Scientific Reports12, 20479 (2022).
  3. The Kinetics of Aragonite Formation from Solution via Amorphous Calcium Carbonate.
    Clark, S., Grigorova, A., Colas, B., Darwish, T., Wood, K., Neufeind, J., Jacob, D.
    Nanomaterials12(23), 4151.
  4. A round-robin approach provides a detailed assessment of biomolecular small-angle scattering data reproducibility and yields consensus curves for benchmarking.
    Trewhella, J., Vachette, P., Bierma, J., Blanchet, C., Brookes, E., Chakravarthy, S., Chatzimagas, L., Cleveland, T., Cowieson, N., Crossett, B., Duff, A., Franke D., Gabel, F., Gillilan, R., Graewert, M., Grishaev, A., Guss, J., Hammel, M., Hopkins, J., Huang, Q., Hub, J., Hura, G., Irving, T., Jeffries, C., Jeong, C., Kirby, N., Krueger, S., Martel, A., Matsui, T., Li, N., Perez, J., Porcar, L., Prange, T., Rajkovic, I., Rocco, M., Rosenberg, D., Ryan, T., Siefert, S., Sekiguchi, H., Svergun, D., Teixeria, S, Thureau, A., Weiss, T., Whitten, A., Wood, K., Zuo, Z.,
    Acta Crystallogr. D. Struct. Biol., 78(11), 1315-1336.
  5. Production and characterisation of modularly deuterated UBE2D1–Ub conjugate by small angle neutron and X-ray scattering.
    Pietras, Z., Duff, A., Morad, V., Wood, K., Jeffries, C. Sunnerhagen, M.
    European Biophysics Journal, 51. 569-577.
  6. NanoSIMS imaging of fatty acid and cholesterol absorption by intestinal enterocytes.
    Chen, K., Song, W., Russell, R., Ferrari, A., Darwish, T., Tontonoz, P., Young, S., Jiang, H.
    JLR Images in Lipid Research, 63(11), 100290.
  7. In-cell DNP NMR reveals multiple targeting effect of antimicrobial peptide.
    Separovic, F., Hofferek, V., Duff, A., McConville, M., Sani, M.
    J. Struct. Biol. X, 6:100074.
  8. Quantitative High-Field NMR- and Mass Spectrometry-Based Fatty Acid Sequencing Reveals Internal Structure in Ru-Catalyzed Deuteration of Docosahexaenoic Acid.
    Wang, D., Vidovic, D., McKay, A., Darwish, T., Park, H., Martinez Garza, S., Shields, S., Brodbelt, J., Wang, Z., Lacombe, R., Shmanai, A., Lysenko, I., Bekish, A., Schmidt, K., Redfield, C., Brenna, J., Shchepinov, M.
    Anal. Chem., 94(38), 12971–12980
  9. Synthesis of Perdeuterated Linoleic Acid-d31 and Chain Deuterated 1-Palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine-d62.
    Moir, M., Yepuri, N., Marshall, D., Blanksby, S., Darwish, T.
    Advanced Synthesis & Catalysis, 364(21), 3670-3681.
  10. The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from Mycobacterium ulcerans and Mycobacterium marinum.
    Ghith, A., Doherty, A., Bruning, J., Russell, R., De Voss, J., Bell, S.
    ACS Infect. Dis., 8(8), 1606-1617.
  11. Human myelin proteolipid protein structure and lipid bilayer stacking.
    Ruskamo, S., Raasakka, A., Pedersen, J., Martel, A., Škubník, K., Darwish, T., Porcar, L., Kursula, P.
    Cell Mol. Life Sci., 79(8), 419.
  12. Selective Oxidations Using a Cytochrome P450 Enzyme Variant Driven with Surrogate Oxygen Donors and Light.
    Lee, J., Podgorski, M., Moir, M., Gee, A., Bell, S.
    Chemistry - A European Journal, 28(49), e202201366.
  13. Expression and purification of the NG domain from human SRα, a key component of the Signal Recognition Particle (SRP) receptor.
    McRae, M., Wang, B., Hyson, E., Siddiquee, R., Duff, A., Ataide, S., Kwan, A.
    Protein Expression and Purification, 198, 106121.
  14. Analysis of the Electric Double Layer Structure Formed in an Ionic Liquid Using Neutron Reflectivity.
    Tamura, K., Akutsu-Suyama, K., Cagnes, M. & Darwish, T.
    ECS Advances, 1, 020503.
  15. “Invisible” Detergents Enable a Reliable Determination of Solution Structures of Native Photosystems by Small-Angle Neutron Scattering.
    Golub, M., Gätcke, J., Subramanian, S., Kölsch , A., Darwish, T., Howard, J. K., Feoktystov, A., Matsarskaia, O., Martel, A., Porcar, L., Zouni, A., Pieper, J.
    J. Phys. Chem. B 2022, 126(15), 2824–2833
  16. Magnetic properties and neutron spectroscopy of lanthanoid-{tetrabromocatecholate/18-crown-6} single-molecule magnets.
    Dunstan, M. A., Cagnes, M., Phonsri, W., Murray, K. S., Mole, R. A. & Boskovic, C.
    Australian Journal of Chemistry, 75(9) 595-609 
  17. Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL.
    Sethi, A., Horne, C. R., Fitzgibbon, C., Wilde, K., Davies, K. A., Garnish, S. E., Jacobsen, A. V., Samson, A. L., Hildebrand, J. M., Wardak, A., Czabotar, P. E., Petrie, E. J., Gooley, P. R. & Murphy, J. M.
    Cell Death & Differentiation.
  18. Strikingly Different Roles of SARS-CoV-2 Fusion Peptides Uncovered by Neutron Scattering.
    Santamaria, A., Batchu, K. C., Matsarskaia, O., Prévost, S. F., Russo, D., Natali, F., Seydel, T., Hoffmann, I., Laux, V., Haertlein, M., Darwish, T. A., Russell, R. A., Corucci, G., Fragneto, G., Maestro, A. & Zaccai, N. R.
    Journal of the American Chemical Society.
  19. Polycation radius of gyration in a polymeric ionic liquid (PIL): the PIL melt is not a theta solvent.
    Wong, L. N., Jones, S. D., Wood, K., de Campo, L., Darwish, T., Moir, M., Li, H., Segalman, R. A., Warr, G. G. & Atkin, R.
    Physical Chemistry Chemical Physics.
  20. Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA.
    Petit, G. A., Mohanty, B., McMahon, R. M., Nebl, S., Hilko, D. H., Wilde, K. L., Scanlon, M. J., Martin, J. L. & Halili, M. A.
    Acta Crystallographica Section D, 78, 75-90.
  21. Mg2+-dependent conformational equilibria in CorA: an integrated view on transport regulation.
    Johansen, N. T., Bonaccorsi, M., Bengtsen, T., Larsen, A. H., Tidemand, F. G., Pedersen, M. C., Huda, P., Berndtsson, J., Darwish, T., Yepuri, N. R., Martel, A., Pomorski, T. G., Bertarello, A., Sansom, M., Rapp, M., Crehuet, R., Schubeis, T., Lindorff-Larsen, K., Pintacuda, G. & Arleth, L.
    eLife 2022;11:e71887


  1. Controlling Phase and Rheological Behaviours of Hexagonal Lyotropic Liquid Crystalline Templates for Nanostructural Administration and Retention.
    Wang, G., Garvey, C. J., Gu, S., Gao, W., O'Dell, L. A., Krause-Heuer, A. M., Darwish, T. A., Zhigunov, A., Tong, X., Kong, L.
    Journal of Colloid and Interface Science.
  2. Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry.
    Luchini, A., Micciulla, S., Corucci, G., Batchu, K. C., Santamaria, A., Laux, V., Darwish, T., Russell, R. A., Thepaut, M., Bally, I., Fieschi, F. & Fragneto, G.
    Scientific Reports, 11, 14867.
  3. H/D Isotope Effects in Keto-Enol Tautomerism of β-Dicarbonyl Compounds —Importance of Nuclear Quantum Effects of Hydrogen Nuclei—.
    Udagawa, T., Murphy, R. B., Darwish, T. A., Tachikawa, M. & Mori, S.
    Bulletin of the Chemical Society of Japan, 94, 1954-1962.
  4. Deuterated Bacterial Cellulose Dissolution in Ionic Liquids.
    Raghuwanshi, V. S., Cohen, Y., Garnier, G., Garvey, C. J. & Garnier, G.
  5. Diffusion in Organic Film Stacks Containing Solution-Processed Phosphorescent Poly(dendrimer) Dopants.
    McEwan, J. A., Clulow, A. J., Nelson, A., Krause-Heuer, A. M., Jansen-van Vuuren, R. D., Burn, P. L. & Gentle, I. R.
    ACS Applied Materials & Interfaces, 13, 30910-30920.
  6. Measuring the Magnetic Field Amplitude of rf Radiation by the Quasistatic Magnetic Field Effect in Organic Light-Emitting Diodes.
    Grünbaum, T., Bange, S., Jiang, W., Leung, A. E., Darwish, T. A., Burn, P. L. & Lupton, J. M.
    Physical Review Applied, 15, 064001.
  7. Kinetic isotope effects and synthetic strategies for deuterated carbon-11 and fluorine-18 labelled PET radiopharmaceuticals.
    Klenner, M. A., Pascali, G., Fraser, B. H. & Darwish, T. A.
    Nuclear Medicine and Biology, 96-97, 112-147.
  8. ApoE and ApoE Nascent-Like HDL Particles at Model Cellular Membranes: Effect of Protein Isoform and Membrane Composition.
    Waldie, S., Sebastiani, F., Moulin, M., Del Giudice, R., Paracini, N., Roosen-Runge, F., Gerelli, Y., Prevost, S., Voss, J. C., Darwish, T. A., Yepuri, N., Pichler, H., Maric, S., Forsyth, V. T., Haertlein, M. & Cárdenas, M.
    Frontiers in Chemistry, 9.
  9. Targeted delivery of LM22A-4 by cubosomes protects retinal ganglion cells in an experimental glaucoma model.
    Ding, Y., Chow, S. H., Chen, J., Brun, A. P. L., Wu, C.-M., Duff, A. P., Wang, Y., Song, J., Wang, J.-H., Wong, V. H. Y., Zhao, D., Nishimura, T., Lee, T.-H., Conn, C. E., Hsu, H.-Y., Bui, B. V., Liu, G.-S. & Shen, H.-H.
    Acta Biomaterialia.
  10. Apolipoprotein E Binding Drives Structural and Compositional Rearrangement of mRNA-Containing Lipid Nanoparticles.
    Sebastiani, F., Yanez Arteta, M., Lerche, M., Porcar, L., Lang, C., Bragg, R. A., Elmore, C. S., Krishnamurthy, V. R., Russell, R. A., Darwish, T., Pichler, H., Waldie, S., Moulin, M., Haertlein, M., Forsyth, V. T., Lindfors, L. & Cárdenas, M.
    ACS Nano.
  11. Substrate-dependent arrangements of the subunits of the BAM complex determined by neutron reflectometry.
    Chen, X., Ding, Y., Bamert, R. S., Le Brun, A. P., Duff, A. P., Wu, C.-M., Hsu, H.-Y., Shiota, T., Lithgow, T. & Shen, H.-H.
    Biochimica et Biophysica Acta (BBA) - Biomembranes, 183587.
  12. Membrane Protein Structures in Lipid Bilayers; Small-Angle Neutron Scattering With Contrast-Matched Bicontinuous Cubic Phases.
    Conn, C. E., de Campo, L., Whitten, A. E., Garvey, C. J., Krause-Heuer, A. M. & van 't Hag, L.
    Frontiers in Chemistry, 8.
  13. Interactions of Non-steroidal Anti-inflammatory Drugs and Their Bismuth Analogues (BiNSAIDs) with Biological Membrane Mimics at Physiological pH.
    Oliver, T. E., Piantavigna, S., Andrews, P. C., Holt, S. A. & Dillon, C. T.
  14. Floquet spin states in OLEDs.
    Jamali, S., Mkhitaryan, V. V., Malissa, H., Nahlawi, A., Popli, H., Grünbaum, T., Bange, S., Milster, S., Stoltzfus, D. M., Leung, A. E., Darwish, T. A., Burn, P. L., Lupton, J. M. & Boehme, C.
    Nature Communications, 12, 465.
  15. Direct localization of detergents and bacteriorhodopsin in the lipidic cubic phase by small-angle neutron scattering.
    Cleveland IV, T., Blick, E., Krueger, S., Leung, A., Darwish, T. & Butler, P.
    IUCrJ, 8.
  16. Metal Catalyzed H/D Exchange Methods Using D2O as a Deuterium Source: A Comparative Study in Different Sealed Devices.
    Akutsu-Suyama, K., Park, K., Takakura, R., Tamura, K., Cagnes, M., Darwish, T. A., Yamada, T., Sawama, Y. & Sajiki, H. 2021.
    Proceedings of the 3rd J-PARC Symposium (J-PARC2019).
    Journal of the Physical Society of Japan.


  1. The Antifungal Mechanism of Amphotericin B Elucidated in Ergosterol and Cholesterol-Containing Membranes Using Neutron Reflectometry.
    Delhom, R., Nelson, A., Laux, V., Haertlein, M., Knecht, W., Fragneto, G. & Wacklin-Knecht, H. P.
    Nanomaterials, 10, 2439. (2020)
  2. Using Humidity to Control the Morphology and Properties of Electrospun BioPEGylated Polyhydroxybutyrate Scaffolds.
    Foster, L. J. R., Chan, R. T. H., Russell, R. A. & Holden, P. J.
    ACS Omega, 5, 26476-26485.
  3. The effect of deuteration on the keto-enol equilibrium and photostability of the sunscreen agent avobenzone.
    Murphy, R., Staton, J., Rawal, A. & Darwish, T. A.
    Photochemical & Photobiological Sciences.
  4. The Aggregation of αB-Crystallin under Crowding Conditions Is Prevented by αA-Crystallin: Implications for α-Crystallin Stability and Lens Transparency.
    Grosas, A. B., Rekas, A., Mata, J. P., Thorn, D. C. & Carver, J. A.
    Journal of Molecular Biology.
  5. NMR fragment screening reveals a novel small molecule binding site near the catalytic surface of the disulfide–dithiol oxidoreductase enzyme DsbA from Burkholderia pseudomallei.
    Nebl, S., Alwan, W. S., Williams, M. L., Sharma, G., Taylor, A., Doak, B. C., Wilde, K. L., McMahon, R. M., Halili, M. A., Martin, J. L., Capuano, B., Fenwick, R. B., Mohanty, B. & Scanlon, M. J.
    Journal of Biomolecular NMR.
  6. Lipoprotein ability to exchange and remove lipids from model membranes as a function of fatty acid saturation and presence of cholesterol.
    Waldie, S., Sebastiani, F., Browning, K., Maric, S., Lind, T. K., Yepuri, N., Darwish, T. A., Moulin, M., Strohmeier, G., Pichler, H., Skoda, M. W. A., Maestro, A., Haertlein, M., Forsyth, V. T., Bengtsson, E., Malmsten, M. & Cárdenas, M.
    Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1865, 158769.
  7. Decagram Scale Production of Deuterated Mineral Oil and Polydecene as Solvents for Polymer Studies in Neutron Scattering.
    Klenner, M. A., Cagnes, M., Wood, K., Mita, K., Mishimoto, M., Darwish, T.
    Polymer Chemistry.
  8. The Location of the Antimicrobial Peptide Maculatin 1.1 in Model Bacterial Membranes.
    Le Brun, A. P., Zhu, S., Sani, M.-A. & Separovic, F.
    Frontiers in Chemistry, 8.
  9. Spontaneous Self-Assembly of Thermoresponsive Vesicles Using a Zwitterionic and an Anionic Surfactant.
    T. McCoy, J. Marlow, A. Armstrong, A. Clulow, C. Garvey, M. Manohar, T. Darwish, B. Boyd, A. Routh, R. Tabor.
  10. Labeled Rhenium Complexes: Radiofluorination, α-MSH Cyclization, and Deuterium Substitutions.
    Klenner, M. A., Darwish, T., Fraser, B., Massi, M., Pascali, G.
  11. Perdeuterated conjugated polymers for ultralow‐frequency magnetic resonance of OLEDs.
    Lupton, J., Milster, S., Bange, S., Kurrman, S., Kraus, H., Stotzfus, D., Burn, P., Leung, A., Darwish, T., Boehme, C.
    Angewandte Chemie International Edition, 59 (24), 9388-9392.
  12. The antimicrobial peptide maculatin self assembles in parallel to form a pore in phospholipid bilayers.
  13. Sani, M.-A., Le Brun, A. P. & Separovic, F.
    Biochimica et Biophysica Acta (BBA) - Biomembranes, 1862, 183204.
  14. Perdeuteration of poly[2-methoxy-5-(2′-ethylhexyloxy)-1,4-phenylenevinylene] (d-MEH-PPV): control of microscopic charge-carrier spin–spin coupling and of magnetic-field effects in optoelectronic devices.
    Stoltzfus, D. M., Joshi, G., Popli, H., Jamali, S., Kavand, M., Milster, S., Grünbaum, T., Bange, S., Nahlawi, A., Teferi, M. Y., Atwood, S. I., Leung, A. E., Darwish, T. A., Malissa, H., Burn, P. L., Lupton, J. M. & Boehme, C.
    Journal of Materials Chemistry C.


  1. Monitoring the phase evolution in LiCoO2 electrodes during battery cycles using in-situ neutron diffraction technique.
    Jena, A., Lee, P.-H., Pang, W. K., Hsiao, K.-C., Peterson, V. K., Darwish, T., Yepuri, N., Wu, S.-H., Chang, H. & Liu, R.-S.
    Journal of the Chinese Chemical Society, 67 (3), 344-352.
  2. Evolution of structural dimensions in mesoporous template precursor from hexagonal lyotropic liquid crystals.
    Wang, G., Garvey, C. J., Zhang, J., LA, O. D., Krause-Heuer, A. M., Forsyth, M., Darwish, T., Steinhart, M. & Kong, L.
    J Phys Condens Matter, 32, 7.
  3. Potential of neutron powder diffraction for the study of solid triacylglycerols.
    Maynard-Casely, H. E., Booth, N., Leung, A. E., Stuart, B. H. & Thomas, P. S.
    Food Structure, 22, 100124.
  4. PEGylation and surface functionalization of liposomes containing drug nanocrystals for cell-targeted delivery.
    Xiao, Y., Liu, Q., Clulow, A. J., Li, T., Manohar, M., Gilbert, E. P., de Campo, L., Hawley, A. & Boyd, B. J.
    Colloids and Surfaces B: Biointerfaces, 182, 110362.
  5. Conformational selection of the intrinsically disordered plant stress protein COR15A in response to solution osmolarity – an X-ray and light
    scattering study.
    Shou, K., Bremer, A., Rindfleisch, T., Knox-Brown, P., Hirai, M., Rekas, A., Garvey, C. J., Hincha, D. K., Stadler, A. M. & Thalhammer, A.
    Physical Chemistry Chemical Physics, 21, 18727-18740.
  6. Controlled deuterium labelling of imidazolium ionic liquids to probe the fine structure of the electrical double layer using neutron reflectometry.
    Akutsu-Suyama, K., Cagnes, M., Tamura, K., Kanaya, T. & Darwish, T. A.
    Physical Chemistry Chemical Physics, 21, 17512-17516.
  7. Multi-dimensional characterization of mixed ligand nanoparticles using small angle neutron scattering
    Luo, Z., Yang, Y., Radulescu, A., Kohlbrecher, J., Darwish, T. A., Ong, Q. K., Guldin, S. & Stellacci, F.
    Chemistry of Materials, 31, 6750-6758.
  8. A Protein-Eye View of the In Meso Crystallization Mechanism
    van 't Hag, L., de Campo, L., Tran, N., Sokolova, A., Trenker, R., Call, M. E., Call, M. J., Garvey, C. J., Leung, A. E., Darwish, T. A., Krause-Heuer, A. M.,
    Knott, R., Meikle, T., Drummond, C. J., Mezzenga, R. & Conn, C. E.
    Langmuir, 35, 8344-8356.
  9. Neutron diffraction of deuterated tripalmitin and the influence of shear on its crystallisation
    Stuart, B. H., Maynard-Casely, H. E., Booth, N., Leung, A. E. & Thomas, P. S.
    Chemistry and Physics of Lipids, 221, 108-113.
  10. Protein Perdeuteration for Neutron Crystallography.
    Duff, A. P.
    Proceedings of the 3rd International Symposium of Quantum Beam Science at Ibaraki University "Quantum Beam Science in Biology and Soft
    Materials (ISQBSS2018)".
  11. A rapid MS/MS method to assess the deuterium kinetic isotope effect and associated improvement in the metabolic stability of deuterated biological and pharmacological molecules as applied to an imaging agent
    Murphy, R. B., Wyatt, N. A., Fraser, B. H., Yepuri, N. R., Holden, P. J., Wotherspoon, A. T. L. & Darwish, T. A.
    Analytica Chimica Acta, 1064, 65-70.
  12. Effect of deuteration on the phase behaviour and structure of lamellar phases of phosphatidylcholines – Deuterated lipids as proxies for the physical properties of native bilayers
    Bryant, G., Taylor, M. B., Darwish, T. A., Krause-Heuer, A. M., Kent, B., Garvey, C. J.
    Colloids and Surfaces B: Biointerfaces, 177, 196-203.
  13. The effects of small molecule organic additives on the self-assembly and rheology of betaine wormlike micellar fluids
    McCoy, T. M., King, J. P., Moore, J. E., Kelleppan, V. T., Sokolova, A. V., de Campo, L., Manohar, M., Darwish, T. A. & Tabor, R. F.
    Journal of Colloid and Interface Science, 534, 518-532.
  14. Studying Munc18:syntaxin interactions using small-angle scattering
    Whitten, A. E., Jarrott, R. J., Hu, S. H., Duff, A. P., King, G. J., Martin, J. L. & Christie, M. P.
    Methods in Molecular Biology.
  15. Deuterated phytantriol – A versatile compound for probing material distribution in liquid crystalline lipid phases using neutron scattering
    ​​​​​Yepuri, N. R., Clulow, A. J., Prentice, R. N., Gilbert, E. P., Hawley, A., Rizwan, S. B., Boyd, B. J. & Darwish, T. A.
    Journal of Colloid and Interface Science, 534, 399-407.


  1. Small-angle neutron scattering studies on the AMPA receptor GluA2 in the resting, AMPA-bound and GYKI-53655-bound states.
    Larsen, A. H., Dorosz, J., Thorsen, T. S., Johansen, N. T., Darwish, T., Midtgaard, S. R., Arleth, L. & Kastrup, J. S.
    IUCrJ, 5, 780-793.
  2. Ionic Liquid Adsorption at the Silica-Oil Interface Revealed by Neutron Reflectometry. 
    Cooper, P. K., Li, H., Yepuri, N. R., Nelson, A., Webber, G. B., Le Brun, A. P., Darwish, T. A., Warr, G. G. & Atkin, R.
    Journal of Physical Chemistry C, 122, 24077-24084.
  3. Mass spectrometry and Monte Carlo method mapping of nanoparticle ligand shell morphology.
    Luo, Z., Zhao, Y., Darwish, T., Wang, Y., Hou, J. & Stellacci, F.
    Nature Communications, 9, 4478.
  4. Annexin V-containing cubosomes for targeted early detection of apoptosis in degenerative retinal tissue
    Ding, Y., Chow, S. H., Liu, G.-S., Wang, B., Lin, T.-W., Hsu, H.-Y., Duff, A. P., Le Brun, A. P. & Shen, H.-H.
    Journal of Materials Chemistry B.
  5. Cellulose Dissolution in Ionic Liquid: Ion Binding Revealed by Neutron Scattering.
    Raghuwanshi, V. S., Cohen, Y., Garnier, G., Garvey, C. J., Russell, R. A., Darwish, T. & Garnier, G.
    Macromolecules, 51, 7649-7655.
  6. BAMLET kills chemotherapy-resistant mesothelioma cells, holding oleic acid in an activated cytotoxic state.
    Rath, E. M., Cheng, Y. Y., Pinese, M., Sarun, K. H., Hudson, A. L., Weir, C., Wang, Y. D., Håkansson, A. P., Howell, V. M., Liu, G. J., Reid, G., Knott, R. B., Duff, A. P. & Bret Church, W. 
    PLoS ONE, 13, e0203003.
  7. Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics.
    Faoro, C., Wilkinson-White, L., Kwan, A. H. & Ataide, S. F.
    PLoS ONE, 13, e0200387.
  8. Comparing Surfactant Structures at “Soft” and “Hard” Hydrophobic Materials: Not All Interfaces Are Equivalent.
    Wei, Z., Piantavigna, S., Holt, S. A., Nelson, A., Spicer, P. T. & Prescott, S. W. 
    Langmuir, 34, 9141-9152.
  9. Solution structure analysis of the periplasmic region of bacterial flagellar motor stators by small angle X-ray scattering.
    Liew, C. W., Hynson, R. M., Ganuelas, L. A., Shah-Mohammadi, N., Duff, A. P., Kojima, S., Homma, M. & Lee, L. K. 
    Biochem Biophys Res Commun, 495, 1614-1619. 
  10. Transient antibody-antigen interactions mediate the strain-specific recognition of a conserved malaria epitope.
    Krishnarjuna, B., Sugiki, T., Morales, R. A. V., Seow, J., Fujiwara, T., Wilde, K. L., Norton, R. S. & MacRaild, C. A. 
    Communications Biology, 1, 58. 
  11. Carbon nanotube mediated miscibility of polyhydroxyalkanoate blends and chemical imaging using deuterium-labelled poly(3-hydroxyoctanoate).
    Russell, R. A., Foster, L. J. R. & Holden, P. J. 
    European Polymer Journal, 105, 150-157. 
  12. Measuring the excitations in a new S = 1/2 quantum spin chain material with competing interactions.
    Rule, K. C., Mole, R. A., Zanardo, J., Krause-Heuer, A., Darwish, T., Lerch, M. & Yu, D. 
    Journal of Physics Condensed Matter, 30, 215602.
  13. Dimensions and Global Twist of Single-Layer DNA Origami Measured by Small-Angle X-ray Scattering
    Baker, M. A. B., Tuckwell, A. J., Berengut, J. F., Bath, J., Benn, F., Duff, A. P., Whitten, A. E., Dunn, K. E., Hynson, R. M., Turberfield, A. J. & Lee, L. K. 
    ACS Nano, 12, 5791-5799. 
  14. Disulfide isomerase activity of the dynamic, trimeric Proteus mirabilis ScsC protein is primed by the tandem immunoglobulin-fold domain of ScsB
    Furlong, E. J., Choudhury, H. G., Kurth, F., Duff, A. P., Whitten, A. E. & Martin, J. L. 
    Journal of Biological Chemistry, 293, 5793-5805. 
  15. Quantitative 3D determination of self-assembled structures on nanoparticles using small angle neutron scattering.
    Luo, Z., Marson, D., Ong, Q. K., Loiudice, A., Kohlbrecher, J., Radulescu, A., Krause-Heuer, A., Darwish, T., Balog, S., Buonsanti, R., Svergun, D. I., Posocco, P. & Stellacci, F. 
    Nature Communications, 9, 1343. 
  16. Penetration behavior of an ionic liquid in thin-layer silica coating: Ionic liquid deuteration and neutron reflectivity analysis.
    Akutsu, K., Cagnes, M., Niizeki, T., Hasegawa, Y. & Darwish, T. A. 
    Physica B: Condensed Matter, 551, 262-265. 
  17. Polymyxin-Induced Lipid A Deacylation in Pseudomonas aeruginosa Perturbs Polymyxin Penetration and Confers High-Level Resistance.
    Han, M. L., Velkov, T., Zhu, Y., Roberts, K. D., Le Brun, A. P., Chow, S. H., Gutu, A. D., Moskowitz, S. M., Shen, H. H. & Li, J.
    ACS Chemical Biology, 13, 121-130.

  18. Invisible detergents for structure determination of membrane proteins by small-angle neutron scattering.
    Midtgaard, S. R., Darwish, T. A., Pedersen, M. C., Huda, P., Larsen, A. H., Jensen, G. V., Kynde, S. A. R., Skar-Gislinge, N., Nielsen, A. J. Z., Olesen, C., Blaise, M., Dorosz, J. J., Thorsen, T. S., Venskutonytė, R., Krintel, C., Møller, J. V., Frielinghaus, H., Gilbert, E. P., Martel, A., Kastrup, J. S., Jensen, P. E., Nissen, P. & Arleth, L. 
    FEBS Journal, 285, 357-371. 

Papers resulting from the Australian Centre for Neutron Scattering user program which utilised the National Deuteration Facility (2011-present)