Modes of access
The National Deuteration Facility offers access to deuterated molecules prepared by both in vivo biodeuteration and chemical deuteration techniques. There are three modes of access to NDF facilities.
An extensive product list is available at below, providing examples of the types of molecules available.
1. Merit based user access
Access to the NDF is most commonly via merit-based proposals.
Dates & submission: Calls for applications close in March and September of each year. NDF staff can assist with the submission process.
Approval & conditions: Proposals are reviewed by a committee and ranked based on scientific merit. The criteria for this mode is that deuterated molecules are to be used for experiments in Australia. Co-authorship on resultant publication/s is required.
Costs: If successful you will receive a grant (no costs) for the deuterated molecule and the beam time (if applicable). There may be some cost recovery negotiated for: multiply-labelled proteins; where there are high costs or shipping; or when there are a large number/quantity of material/s requested.
Delivery: The time-frame for delivery of the materials is via negotiation, however, proposals are usually submitted for commencement in the next 6 month block (i.e. March submission for July commencement, September for January commencement).
2. User pays/collaboration mode of access
Dates & submission: This mode is for proposals outside the regular user program round.
Approval & conditions: Submission of a short proposal is required to allow for internal assessment. Co-authorship on resulting publication/s is also expected for this access mode.
Costs: NDF can by negotiation provide deuterated materials under a user pays/collaboration arrangement, where there is 50% cost recovery of materials and labour are involved.
Proposals from applicants in countries other than Australia will be subject to a cost recovery fee unless the molecules are for use in experiments in Australia.
Delivery: dates are by negotiation.
3. Commercial access
Dates & submission: Enquires accepted at any time. NDF will internally manage any proposal submission under this mode.
Approval & conditions: Approval is by NDF Leader discretion. NDF acknowledgement on any resultant publication/s is requested.
Costs: Full cost recovery.
Delivery: dates by negotiation.
Certificate of Analysis/Product Data Sheet
For successful proposals, NDF will synthesise and provide the requested deuterated molecules or materials, provide chemical and biological advice and provide the appropriate analyses for the produced deuterated product (e.g., certificate of analysis or product data sheet). Figures/experimental data will also be provided for manuscripts where co-authorship has been negotiated.
The National Deuteration Facility is partly supported by the National Collaborative Research Infrastructure Strategy – an initiative of the Australian Government.