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Deuteration
Instruments

Deuteration

Chemical and biological deuteration at the National Deuteration facility enables complex investigations of the relationship between the structure of molecules and their function using neutron scattering and other techniques.

The National Deuteration Facility offers the facilities, staff and expertise to produce molecules where all or part of the the molecular hydrogen is in the form of deuterium (2H or D).

The facility produces deuterated proteins, biolpolymers, nucleic acids and synthesises small organic molecules  such as lipids, phospholipids, , sugars, surfactants, aliphatic hydrocarbons and aromatic, heterocyclic compounds. Double and triple labelling of proteins with both deuterium and the stable isotopes carbon-13 and/or nitrogen-15, are alko available. 

The facility offers molecular deuteration using either in vivo biodeuteration or chemical deuteration techniques.